Arginine demethylation is catalysed by a subset of JmjC histone lysine demethylases

While reversal of lysine methylation on histone tails is a well-established mechanism to tune gene expression, the existence of a similar arginine demethylation process is controversial. Here, the authors show that some jumonji enzymes possess both lysine and arginine demethylase activity in vitro.

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Autores principales:	Louise J. Walport, Richard J. Hopkinson, Rasheduzzaman Chowdhury, Rachel Schiller, Wei Ge, Akane Kawamura, Christopher J. Schofield
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/b3dc6971dc6349f5a32b481bb23ad534
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spelling	oai:doaj.org-article:b3dc6971dc6349f5a32b481bb23ad5342021-12-02T15:34:10ZArginine demethylation is catalysed by a subset of JmjC histone lysine demethylases10.1038/ncomms119742041-1723https://doaj.org/article/b3dc6971dc6349f5a32b481bb23ad5342016-06-01T00:00:00Zhttps://doi.org/10.1038/ncomms11974https://doaj.org/toc/2041-1723While reversal of lysine methylation on histone tails is a well-established mechanism to tune gene expression, the existence of a similar arginine demethylation process is controversial. Here, the authors show that some jumonji enzymes possess both lysine and arginine demethylase activity in vitro.Louise J. WalportRichard J. HopkinsonRasheduzzaman ChowdhuryRachel SchillerWei GeAkane KawamuraChristopher J. SchofieldNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-12 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Louise J. Walport Richard J. Hopkinson Rasheduzzaman Chowdhury Rachel Schiller Wei Ge Akane Kawamura Christopher J. Schofield Arginine demethylation is catalysed by a subset of JmjC histone lysine demethylases
description	While reversal of lysine methylation on histone tails is a well-established mechanism to tune gene expression, the existence of a similar arginine demethylation process is controversial. Here, the authors show that some jumonji enzymes possess both lysine and arginine demethylase activity in vitro.
format	article
author	Louise J. Walport Richard J. Hopkinson Rasheduzzaman Chowdhury Rachel Schiller Wei Ge Akane Kawamura Christopher J. Schofield
author_facet	Louise J. Walport Richard J. Hopkinson Rasheduzzaman Chowdhury Rachel Schiller Wei Ge Akane Kawamura Christopher J. Schofield
author_sort	Louise J. Walport
title	Arginine demethylation is catalysed by a subset of JmjC histone lysine demethylases
title_short	Arginine demethylation is catalysed by a subset of JmjC histone lysine demethylases
title_full	Arginine demethylation is catalysed by a subset of JmjC histone lysine demethylases
title_fullStr	Arginine demethylation is catalysed by a subset of JmjC histone lysine demethylases
title_full_unstemmed	Arginine demethylation is catalysed by a subset of JmjC histone lysine demethylases
title_sort	arginine demethylation is catalysed by a subset of jmjc histone lysine demethylases
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/b3dc6971dc6349f5a32b481bb23ad534
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Arginine demethylation is catalysed by a subset of JmjC histone lysine demethylases

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