Inference of differentiation time for single cell transcriptomes using cell population reference data

Single cell transcriptome data can be used to determine developmental lineage trajectories. Here the authors map single cell transcriptomes onto a differentiation trajectory defined by cell population transcriptomes and show that cell cycle regulators have a role in differentiation timing.

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Autores principales: Na Sun, Xiaoming Yu, Fang Li, Denghui Liu, Shengbao Suo, Weiyang Chen, Shirui Chen, Lu Song, Christopher D. Green, Joseph McDermott, Qin Shen, Naihe Jing, Jing-Dong J. Han
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Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/b3dce32d074f4befabf8d32b355f38cb
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spelling oai:doaj.org-article:b3dce32d074f4befabf8d32b355f38cb2021-12-02T14:42:00ZInference of differentiation time for single cell transcriptomes using cell population reference data10.1038/s41467-017-01860-22041-1723https://doaj.org/article/b3dce32d074f4befabf8d32b355f38cb2017-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-01860-2https://doaj.org/toc/2041-1723Single cell transcriptome data can be used to determine developmental lineage trajectories. Here the authors map single cell transcriptomes onto a differentiation trajectory defined by cell population transcriptomes and show that cell cycle regulators have a role in differentiation timing.Na SunXiaoming YuFang LiDenghui LiuShengbao SuoWeiyang ChenShirui ChenLu SongChristopher D. GreenJoseph McDermottQin ShenNaihe JingJing-Dong J. HanNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Na Sun
Xiaoming Yu
Fang Li
Denghui Liu
Shengbao Suo
Weiyang Chen
Shirui Chen
Lu Song
Christopher D. Green
Joseph McDermott
Qin Shen
Naihe Jing
Jing-Dong J. Han
Inference of differentiation time for single cell transcriptomes using cell population reference data
description Single cell transcriptome data can be used to determine developmental lineage trajectories. Here the authors map single cell transcriptomes onto a differentiation trajectory defined by cell population transcriptomes and show that cell cycle regulators have a role in differentiation timing.
format article
author Na Sun
Xiaoming Yu
Fang Li
Denghui Liu
Shengbao Suo
Weiyang Chen
Shirui Chen
Lu Song
Christopher D. Green
Joseph McDermott
Qin Shen
Naihe Jing
Jing-Dong J. Han
author_facet Na Sun
Xiaoming Yu
Fang Li
Denghui Liu
Shengbao Suo
Weiyang Chen
Shirui Chen
Lu Song
Christopher D. Green
Joseph McDermott
Qin Shen
Naihe Jing
Jing-Dong J. Han
author_sort Na Sun
title Inference of differentiation time for single cell transcriptomes using cell population reference data
title_short Inference of differentiation time for single cell transcriptomes using cell population reference data
title_full Inference of differentiation time for single cell transcriptomes using cell population reference data
title_fullStr Inference of differentiation time for single cell transcriptomes using cell population reference data
title_full_unstemmed Inference of differentiation time for single cell transcriptomes using cell population reference data
title_sort inference of differentiation time for single cell transcriptomes using cell population reference data
publisher Nature Portfolio
publishDate 2017
url https://doaj.org/article/b3dce32d074f4befabf8d32b355f38cb
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