Clinical implication of bactibilia in moderate to severe acute cholecystitis undergone cholecystostomy following cholecystectomy

Abstract There is little evidence of clinical outcome in using antibiotics during the perioperative phase of acute cholecystitis with bactibilia. The aim of current study is to examine the effect of bactibilia on patients with acute cholecystitis and their perioperative clinical outcome. We performe...

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Autores principales:	Je Ho Yoon, Kwang Yeol Paik, Hoo Young Chung, Ji Seon Oh
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/b3f0718ef6fd4008b0d0eca041a23137
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spelling	oai:doaj.org-article:b3f0718ef6fd4008b0d0eca041a231372021-12-02T15:03:13ZClinical implication of bactibilia in moderate to severe acute cholecystitis undergone cholecystostomy following cholecystectomy10.1038/s41598-021-91261-92045-2322https://doaj.org/article/b3f0718ef6fd4008b0d0eca041a231372021-06-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-91261-9https://doaj.org/toc/2045-2322Abstract There is little evidence of clinical outcome in using antibiotics during the perioperative phase of acute cholecystitis with bactibilia. The aim of current study is to examine the effect of bactibilia on patients with acute cholecystitis and their perioperative clinical outcome. We performed a retrospective cohort analysis of 128 patients who underwent cholecystectomy for acute cholecystitis with moderate and severe grade. Patients who were positive for bactibilia were compared to bactibilia-negative group in following categories: morbidity, duration of antimicrobial agent use, in-hospital course, and readmission rate. There was no difference in morbidity when patients with bactibilia (n = 70) were compared to those without (n = 58) after cholecystectomy. The duration of antibiotics use and clinical course were also similar in both groups. In severe grade AC group (n = 18), patients used antibiotics and were hospitalized for a significantly longer period of time than those in the moderate grade AC group. The morbidity including surgical site infection, and readmission rates were not significantly different in moderate and severe grade AC groups. In moderate and severe AC groups, bactibilia itself did not predict more complication and worse clinical course. Antibiotics may be safely discontinued within few days after cholecystectomy irrespective of bactibilia when cholecystectomy is successful.Je Ho YoonKwang Yeol PaikHoo Young ChungJi Seon OhNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-6 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Je Ho Yoon Kwang Yeol Paik Hoo Young Chung Ji Seon Oh Clinical implication of bactibilia in moderate to severe acute cholecystitis undergone cholecystostomy following cholecystectomy
description	Abstract There is little evidence of clinical outcome in using antibiotics during the perioperative phase of acute cholecystitis with bactibilia. The aim of current study is to examine the effect of bactibilia on patients with acute cholecystitis and their perioperative clinical outcome. We performed a retrospective cohort analysis of 128 patients who underwent cholecystectomy for acute cholecystitis with moderate and severe grade. Patients who were positive for bactibilia were compared to bactibilia-negative group in following categories: morbidity, duration of antimicrobial agent use, in-hospital course, and readmission rate. There was no difference in morbidity when patients with bactibilia (n = 70) were compared to those without (n = 58) after cholecystectomy. The duration of antibiotics use and clinical course were also similar in both groups. In severe grade AC group (n = 18), patients used antibiotics and were hospitalized for a significantly longer period of time than those in the moderate grade AC group. The morbidity including surgical site infection, and readmission rates were not significantly different in moderate and severe grade AC groups. In moderate and severe AC groups, bactibilia itself did not predict more complication and worse clinical course. Antibiotics may be safely discontinued within few days after cholecystectomy irrespective of bactibilia when cholecystectomy is successful.
format	article
author	Je Ho Yoon Kwang Yeol Paik Hoo Young Chung Ji Seon Oh
author_facet	Je Ho Yoon Kwang Yeol Paik Hoo Young Chung Ji Seon Oh
author_sort	Je Ho Yoon
title	Clinical implication of bactibilia in moderate to severe acute cholecystitis undergone cholecystostomy following cholecystectomy
title_short	Clinical implication of bactibilia in moderate to severe acute cholecystitis undergone cholecystostomy following cholecystectomy
title_full	Clinical implication of bactibilia in moderate to severe acute cholecystitis undergone cholecystostomy following cholecystectomy
title_fullStr	Clinical implication of bactibilia in moderate to severe acute cholecystitis undergone cholecystostomy following cholecystectomy
title_full_unstemmed	Clinical implication of bactibilia in moderate to severe acute cholecystitis undergone cholecystostomy following cholecystectomy
title_sort	clinical implication of bactibilia in moderate to severe acute cholecystitis undergone cholecystostomy following cholecystectomy
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/b3f0718ef6fd4008b0d0eca041a23137
work_keys_str_mv	AT jehoyoon clinicalimplicationofbactibiliainmoderatetosevereacutecholecystitisundergonecholecystostomyfollowingcholecystectomy AT kwangyeolpaik clinicalimplicationofbactibiliainmoderatetosevereacutecholecystitisundergonecholecystostomyfollowingcholecystectomy AT hooyoungchung clinicalimplicationofbactibiliainmoderatetosevereacutecholecystitisundergonecholecystostomyfollowingcholecystectomy AT jiseonoh clinicalimplicationofbactibiliainmoderatetosevereacutecholecystitisundergonecholecystostomyfollowingcholecystectomy
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Clinical implication of bactibilia in moderate to severe acute cholecystitis undergone cholecystostomy following cholecystectomy

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