Chiral DOTA chelators as an improved platform for biomedical imaging and therapy applications
MRI contrast agents containing the rare earth metal gadolinium are very effective, yet unstable and thus potentially hazardous. Here, the authors developed complexes between gadolinium and the scaffolding compound DOTA with increased stability, which also lend themselves to radiometal labelling.
Guardado en:
Autores principales: | Lixiong Dai, Chloe M. Jones, Wesley Ting Kwok Chan, Tiffany A. Pham, Xiaoxi Ling, Eric M. Gale, Nicholas J. Rotile, William Chi-Shing Tai, Carolyn J. Anderson, Peter Caravan, Ga-Lai Law |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2018
|
Materias: | |
Acceso en línea: | https://doaj.org/article/b3f0ee3971b54efaad568f148589af0b |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
A Chelate-Free Nano-Platform for Incorporation of Diagnostic and Therapeutic Isotopes
por: Gholami YH, et al.
Publicado: (2020) -
Giant single-crystal-to-single-crystal transformations associated with chiral interconversion induced by elimination of chelating ligands
por: Yun Li, et al.
Publicado: (2021) -
Helicate-to-tetrahedron transformation of chiral lanthanide supramolecular complexes induced by ionic radii effect and linker length
por: King-Him Yim, et al.
Publicado: (2021) -
Human sample authentication in biomedical research: comparison of two platforms
por: Harshitha Shobha Manjunath, et al.
Publicado: (2021) -
Resilin-mimetics as a smart biomaterial platform for biomedical applications
por: Rajkamal Balu, et al.
Publicado: (2021)