Chiral DOTA chelators as an improved platform for biomedical imaging and therapy applications

MRI contrast agents containing the rare earth metal gadolinium are very effective, yet unstable and thus potentially hazardous. Here, the authors developed complexes between gadolinium and the scaffolding compound DOTA with increased stability, which also lend themselves to radiometal labelling.

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Detalles Bibliográficos
Autores principales: Lixiong Dai, Chloe M. Jones, Wesley Ting Kwok Chan, Tiffany A. Pham, Xiaoxi Ling, Eric M. Gale, Nicholas J. Rotile, William Chi-Shing Tai, Carolyn J. Anderson, Peter Caravan, Ga-Lai Law
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/b3f0ee3971b54efaad568f148589af0b
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