Genomic alterations associated with mutational signatures, DNA damage repair and chromatin remodeling pathways in cervical carcinoma

Genomic alterations associated with mutational signatures, DNA damage repair and chromatin remodeling pathways in cervical carcinoma

Abstract Despite recent advances in the prevention of cervical cancer, the disease remains a leading cause of cancer-related deaths in women worldwide. By applying the GISTIC2.0 and/or the MutSig2CV algorithms on 430 whole-exome-sequenced cervical carcinomas, we identified previously unreported sign...

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Bibliographic Details
Main Authors: Mari K. Halle, Aishwarya Sundaresan, Jianqing Zhang, Chandra Sekhar Pedamallu, Vinodh Srinivasasainagendra, Jessica Blair, Dewey Brooke, Bjørn I. Bertelsen, Kathrine Woie, Sadeep Shrestha, Hemant Tiwari, Yick Fu Wong, Camilla Krakstad, Akinyemi I. Ojesina
Format: article
Language:EN
Published: Nature Portfolio 2021
Subjects:
Medicine
R
Genetics
QH426-470
Online Access:https://doaj.org/article/b3ff1a185aaf4482bae4d581122715c0
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