Dendritic cell-induced activation of latent HIV-1 provirus in actively proliferating primary T lymphocytes.
HIV-1 latency remains a formidable barrier towards virus eradication as therapeutic attempts to purge these reservoirs are so far unsuccessful. The pool of transcriptionally silent proviruses is established early in infection and persists for a lifetime, even when viral loads are suppressed below de...
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Main Authors: | Renée M van der Sluis, Thijs van Montfort, Georgios Pollakis, Rogier W Sanders, Dave Speijer, Ben Berkhout, Rienk E Jeeninga |
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Format: | article |
Language: | EN |
Published: |
Public Library of Science (PLoS)
2013
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Online Access: | https://doaj.org/article/b40168c1079a4ba495516c81e01e3a63 |
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