Dendritic cell-induced activation of latent HIV-1 provirus in actively proliferating primary T lymphocytes.

HIV-1 latency remains a formidable barrier towards virus eradication as therapeutic attempts to purge these reservoirs are so far unsuccessful. The pool of transcriptionally silent proviruses is established early in infection and persists for a lifetime, even when viral loads are suppressed below de...

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Auteurs principaux: Renée M van der Sluis, Thijs van Montfort, Georgios Pollakis, Rogier W Sanders, Dave Speijer, Ben Berkhout, Rienk E Jeeninga
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2013
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Accès en ligne:https://doaj.org/article/b40168c1079a4ba495516c81e01e3a63
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