Oxytocin administration for induction and augmentation of labour in polish maternity units – an observational study

Abstract Background There is not enough data regarding practices and protocols on the dose of oxytocin administrated to women during labour. Empirical evidence indicates that compliance with the guidelines improves the quality of healthcare and reduces adverse effects. The study aimed to evaluate pr...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Barbara Baranowska, Anna Kajdy, Iwona Kiersnowska, Dorota Sys, Urszula Tataj-Puzyna, Déirdre Daly, Michał Rabijewski, Grażyna Bączek, Maria Węgrzynowska
Formato: article
Lenguaje:EN
Publicado: BMC 2021
Materias:
Acceso en línea:https://doaj.org/article/b406761b862e449fb908c70a1ff61979
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
id oai:doaj.org-article:b406761b862e449fb908c70a1ff61979
record_format dspace
spelling oai:doaj.org-article:b406761b862e449fb908c70a1ff619792021-11-14T12:32:32ZOxytocin administration for induction and augmentation of labour in polish maternity units – an observational study10.1186/s12884-021-04190-w1471-2393https://doaj.org/article/b406761b862e449fb908c70a1ff619792021-11-01T00:00:00Zhttps://doi.org/10.1186/s12884-021-04190-whttps://doaj.org/toc/1471-2393Abstract Background There is not enough data regarding practices and protocols on the dose of oxytocin administrated to women during labour. Empirical evidence indicates that compliance with the guidelines improves the quality of healthcare and reduces adverse effects. The study aimed to evaluate practices of oxytocin provision for labour induction and augmentation in two maternity units in Poland. Methods The article presents a prospective observational study. Data from 545 (n = 545) labours was collected in two maternity units. First, the total dose (the total amount of oxytocin provided from the beginning in the labour ward until delivery including the III and IV stage of labour) and cumulative dose of oxytocin (the amount of oxytocin given until the birth of the neonate) administered to women during labour was calculated. Then, the relationship between the cumulative dose of oxytocin and short term perinatal outcomes (mode of delivery, use of epidural anaesthesia, Apgar scores, birth weight and postpartum blood loss) was analysed. Finally, the compliance of oxytocin supply during labour with national guidelines in the following five criteria: medium, start dose, escalation rate, interval, the continuation of infusion after established labour was examined. Results The average cumulative dose of oxytocin administrated to women before birth was 4402 mU following labour induction and 2366 mU following labour augmentation. The actual administration of oxytocin deviated both from the unit and national guidelines in 93.6% of all observed labours (mainly because of continuation of infusion after established labour). We found no statistically significant correlation between the cumulative dose of oxytocin administered and mode of delivery, immediate postpartum blood loss or Apgar scores. There was no observed effect of cumulative dose oxytocin on short-term perinatal outcomes. The two units participating in the study had similar protocols and did not differ significantly in terms of total oxytocin dose, rates of induction and augmentation - the only observed difference was the mode of delivery. Conclusions The study showed no effect of the mean cumulative oxytocin dose on short-term perinatal outcomes and high rate of non-compliance of the practice of oxytocin administration for labour induction and augmentation with the national recommendations. Cooperation between different professional groups of maternity care providers should be considered in building national guidelines for maternity care.. Further studies investigating possible long-term effects of the meant cumulative dose of oxytocin and the reasons for non-compliance of practice with guidelines should be carried out.Barbara BaranowskaAnna KajdyIwona KiersnowskaDorota SysUrszula Tataj-PuzynaDéirdre DalyMichał RabijewskiGrażyna BączekMaria WęgrzynowskaBMCarticleOxytocinLabourInductionAugmentationPractice protocolGynecology and obstetricsRG1-991ENBMC Pregnancy and Childbirth, Vol 21, Iss 1, Pp 1-9 (2021)
institution DOAJ
collection DOAJ
language EN
topic Oxytocin
Labour
Induction
Augmentation
Practice protocol
Gynecology and obstetrics
RG1-991
spellingShingle Oxytocin
Labour
Induction
Augmentation
Practice protocol
Gynecology and obstetrics
RG1-991
Barbara Baranowska
Anna Kajdy
Iwona Kiersnowska
Dorota Sys
Urszula Tataj-Puzyna
Déirdre Daly
Michał Rabijewski
Grażyna Bączek
Maria Węgrzynowska
Oxytocin administration for induction and augmentation of labour in polish maternity units – an observational study
description Abstract Background There is not enough data regarding practices and protocols on the dose of oxytocin administrated to women during labour. Empirical evidence indicates that compliance with the guidelines improves the quality of healthcare and reduces adverse effects. The study aimed to evaluate practices of oxytocin provision for labour induction and augmentation in two maternity units in Poland. Methods The article presents a prospective observational study. Data from 545 (n = 545) labours was collected in two maternity units. First, the total dose (the total amount of oxytocin provided from the beginning in the labour ward until delivery including the III and IV stage of labour) and cumulative dose of oxytocin (the amount of oxytocin given until the birth of the neonate) administered to women during labour was calculated. Then, the relationship between the cumulative dose of oxytocin and short term perinatal outcomes (mode of delivery, use of epidural anaesthesia, Apgar scores, birth weight and postpartum blood loss) was analysed. Finally, the compliance of oxytocin supply during labour with national guidelines in the following five criteria: medium, start dose, escalation rate, interval, the continuation of infusion after established labour was examined. Results The average cumulative dose of oxytocin administrated to women before birth was 4402 mU following labour induction and 2366 mU following labour augmentation. The actual administration of oxytocin deviated both from the unit and national guidelines in 93.6% of all observed labours (mainly because of continuation of infusion after established labour). We found no statistically significant correlation between the cumulative dose of oxytocin administered and mode of delivery, immediate postpartum blood loss or Apgar scores. There was no observed effect of cumulative dose oxytocin on short-term perinatal outcomes. The two units participating in the study had similar protocols and did not differ significantly in terms of total oxytocin dose, rates of induction and augmentation - the only observed difference was the mode of delivery. Conclusions The study showed no effect of the mean cumulative oxytocin dose on short-term perinatal outcomes and high rate of non-compliance of the practice of oxytocin administration for labour induction and augmentation with the national recommendations. Cooperation between different professional groups of maternity care providers should be considered in building national guidelines for maternity care.. Further studies investigating possible long-term effects of the meant cumulative dose of oxytocin and the reasons for non-compliance of practice with guidelines should be carried out.
format article
author Barbara Baranowska
Anna Kajdy
Iwona Kiersnowska
Dorota Sys
Urszula Tataj-Puzyna
Déirdre Daly
Michał Rabijewski
Grażyna Bączek
Maria Węgrzynowska
author_facet Barbara Baranowska
Anna Kajdy
Iwona Kiersnowska
Dorota Sys
Urszula Tataj-Puzyna
Déirdre Daly
Michał Rabijewski
Grażyna Bączek
Maria Węgrzynowska
author_sort Barbara Baranowska
title Oxytocin administration for induction and augmentation of labour in polish maternity units – an observational study
title_short Oxytocin administration for induction and augmentation of labour in polish maternity units – an observational study
title_full Oxytocin administration for induction and augmentation of labour in polish maternity units – an observational study
title_fullStr Oxytocin administration for induction and augmentation of labour in polish maternity units – an observational study
title_full_unstemmed Oxytocin administration for induction and augmentation of labour in polish maternity units – an observational study
title_sort oxytocin administration for induction and augmentation of labour in polish maternity units – an observational study
publisher BMC
publishDate 2021
url https://doaj.org/article/b406761b862e449fb908c70a1ff61979
work_keys_str_mv AT barbarabaranowska oxytocinadministrationforinductionandaugmentationoflabourinpolishmaternityunitsanobservationalstudy
AT annakajdy oxytocinadministrationforinductionandaugmentationoflabourinpolishmaternityunitsanobservationalstudy
AT iwonakiersnowska oxytocinadministrationforinductionandaugmentationoflabourinpolishmaternityunitsanobservationalstudy
AT dorotasys oxytocinadministrationforinductionandaugmentationoflabourinpolishmaternityunitsanobservationalstudy
AT urszulatatajpuzyna oxytocinadministrationforinductionandaugmentationoflabourinpolishmaternityunitsanobservationalstudy
AT deirdredaly oxytocinadministrationforinductionandaugmentationoflabourinpolishmaternityunitsanobservationalstudy
AT michałrabijewski oxytocinadministrationforinductionandaugmentationoflabourinpolishmaternityunitsanobservationalstudy
AT grazynabaczek oxytocinadministrationforinductionandaugmentationoflabourinpolishmaternityunitsanobservationalstudy
AT mariawegrzynowska oxytocinadministrationforinductionandaugmentationoflabourinpolishmaternityunitsanobservationalstudy
_version_ 1718429188426301440