Divergent wiring of repressive and active chromatin interactions between mouse embryonic and trophoblast lineages
The role of the genome structure in the establishment of the embryonic and trophoblast lineages is still not well understood. Here the authors perform promoter capture Hi-C in mouse trophoblast and embryonic stem cells and find divergent networks of repressive and active chromatin interactions betwe...
Guardado en:
Autores principales: | , , , , , , , |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2018
|
Materias: | |
Acceso en línea: | https://doaj.org/article/b406d78bb61b40df9e736ae3f1f1e49a |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
id |
oai:doaj.org-article:b406d78bb61b40df9e736ae3f1f1e49a |
---|---|
record_format |
dspace |
spelling |
oai:doaj.org-article:b406d78bb61b40df9e736ae3f1f1e49a2021-12-02T17:31:29ZDivergent wiring of repressive and active chromatin interactions between mouse embryonic and trophoblast lineages10.1038/s41467-018-06666-42041-1723https://doaj.org/article/b406d78bb61b40df9e736ae3f1f1e49a2018-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-06666-4https://doaj.org/toc/2041-1723The role of the genome structure in the establishment of the embryonic and trophoblast lineages is still not well understood. Here the authors perform promoter capture Hi-C in mouse trophoblast and embryonic stem cells and find divergent networks of repressive and active chromatin interactions between the two lineages.Stefan SchoenfelderBorbala MifsudClaire E. SennerChristopher D. ToddStephanie ChrysanthouElodie DarboMyriam HembergerMiguel R. BrancoNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-10 (2018) |
institution |
DOAJ |
collection |
DOAJ |
language |
EN |
topic |
Science Q |
spellingShingle |
Science Q Stefan Schoenfelder Borbala Mifsud Claire E. Senner Christopher D. Todd Stephanie Chrysanthou Elodie Darbo Myriam Hemberger Miguel R. Branco Divergent wiring of repressive and active chromatin interactions between mouse embryonic and trophoblast lineages |
description |
The role of the genome structure in the establishment of the embryonic and trophoblast lineages is still not well understood. Here the authors perform promoter capture Hi-C in mouse trophoblast and embryonic stem cells and find divergent networks of repressive and active chromatin interactions between the two lineages. |
format |
article |
author |
Stefan Schoenfelder Borbala Mifsud Claire E. Senner Christopher D. Todd Stephanie Chrysanthou Elodie Darbo Myriam Hemberger Miguel R. Branco |
author_facet |
Stefan Schoenfelder Borbala Mifsud Claire E. Senner Christopher D. Todd Stephanie Chrysanthou Elodie Darbo Myriam Hemberger Miguel R. Branco |
author_sort |
Stefan Schoenfelder |
title |
Divergent wiring of repressive and active chromatin interactions between mouse embryonic and trophoblast lineages |
title_short |
Divergent wiring of repressive and active chromatin interactions between mouse embryonic and trophoblast lineages |
title_full |
Divergent wiring of repressive and active chromatin interactions between mouse embryonic and trophoblast lineages |
title_fullStr |
Divergent wiring of repressive and active chromatin interactions between mouse embryonic and trophoblast lineages |
title_full_unstemmed |
Divergent wiring of repressive and active chromatin interactions between mouse embryonic and trophoblast lineages |
title_sort |
divergent wiring of repressive and active chromatin interactions between mouse embryonic and trophoblast lineages |
publisher |
Nature Portfolio |
publishDate |
2018 |
url |
https://doaj.org/article/b406d78bb61b40df9e736ae3f1f1e49a |
work_keys_str_mv |
AT stefanschoenfelder divergentwiringofrepressiveandactivechromatininteractionsbetweenmouseembryonicandtrophoblastlineages AT borbalamifsud divergentwiringofrepressiveandactivechromatininteractionsbetweenmouseembryonicandtrophoblastlineages AT claireesenner divergentwiringofrepressiveandactivechromatininteractionsbetweenmouseembryonicandtrophoblastlineages AT christopherdtodd divergentwiringofrepressiveandactivechromatininteractionsbetweenmouseembryonicandtrophoblastlineages AT stephaniechrysanthou divergentwiringofrepressiveandactivechromatininteractionsbetweenmouseembryonicandtrophoblastlineages AT elodiedarbo divergentwiringofrepressiveandactivechromatininteractionsbetweenmouseembryonicandtrophoblastlineages AT myriamhemberger divergentwiringofrepressiveandactivechromatininteractionsbetweenmouseembryonicandtrophoblastlineages AT miguelrbranco divergentwiringofrepressiveandactivechromatininteractionsbetweenmouseembryonicandtrophoblastlineages |
_version_ |
1718380634138738688 |