Divergent wiring of repressive and active chromatin interactions between mouse embryonic and trophoblast lineages

The role of the genome structure in the establishment of the embryonic and trophoblast lineages is still not well understood. Here the authors perform promoter capture Hi-C in mouse trophoblast and embryonic stem cells and find divergent networks of repressive and active chromatin interactions betwe...

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Autores principales: Stefan Schoenfelder, Borbala Mifsud, Claire E. Senner, Christopher D. Todd, Stephanie Chrysanthou, Elodie Darbo, Myriam Hemberger, Miguel R. Branco
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Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/b406d78bb61b40df9e736ae3f1f1e49a
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spelling oai:doaj.org-article:b406d78bb61b40df9e736ae3f1f1e49a2021-12-02T17:31:29ZDivergent wiring of repressive and active chromatin interactions between mouse embryonic and trophoblast lineages10.1038/s41467-018-06666-42041-1723https://doaj.org/article/b406d78bb61b40df9e736ae3f1f1e49a2018-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-06666-4https://doaj.org/toc/2041-1723The role of the genome structure in the establishment of the embryonic and trophoblast lineages is still not well understood. Here the authors perform promoter capture Hi-C in mouse trophoblast and embryonic stem cells and find divergent networks of repressive and active chromatin interactions between the two lineages.Stefan SchoenfelderBorbala MifsudClaire E. SennerChristopher D. ToddStephanie ChrysanthouElodie DarboMyriam HembergerMiguel R. BrancoNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-10 (2018)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Stefan Schoenfelder
Borbala Mifsud
Claire E. Senner
Christopher D. Todd
Stephanie Chrysanthou
Elodie Darbo
Myriam Hemberger
Miguel R. Branco
Divergent wiring of repressive and active chromatin interactions between mouse embryonic and trophoblast lineages
description The role of the genome structure in the establishment of the embryonic and trophoblast lineages is still not well understood. Here the authors perform promoter capture Hi-C in mouse trophoblast and embryonic stem cells and find divergent networks of repressive and active chromatin interactions between the two lineages.
format article
author Stefan Schoenfelder
Borbala Mifsud
Claire E. Senner
Christopher D. Todd
Stephanie Chrysanthou
Elodie Darbo
Myriam Hemberger
Miguel R. Branco
author_facet Stefan Schoenfelder
Borbala Mifsud
Claire E. Senner
Christopher D. Todd
Stephanie Chrysanthou
Elodie Darbo
Myriam Hemberger
Miguel R. Branco
author_sort Stefan Schoenfelder
title Divergent wiring of repressive and active chromatin interactions between mouse embryonic and trophoblast lineages
title_short Divergent wiring of repressive and active chromatin interactions between mouse embryonic and trophoblast lineages
title_full Divergent wiring of repressive and active chromatin interactions between mouse embryonic and trophoblast lineages
title_fullStr Divergent wiring of repressive and active chromatin interactions between mouse embryonic and trophoblast lineages
title_full_unstemmed Divergent wiring of repressive and active chromatin interactions between mouse embryonic and trophoblast lineages
title_sort divergent wiring of repressive and active chromatin interactions between mouse embryonic and trophoblast lineages
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/b406d78bb61b40df9e736ae3f1f1e49a
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AT claireesenner divergentwiringofrepressiveandactivechromatininteractionsbetweenmouseembryonicandtrophoblastlineages
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AT myriamhemberger divergentwiringofrepressiveandactivechromatininteractionsbetweenmouseembryonicandtrophoblastlineages
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