The sugar-responsive enteroendocrine neuropeptide F regulates lipid metabolism through glucagon-like and insulin-like hormones in Drosophila melanogaster

Incretin hormones regulate insulin and glucagon secretion in mammals, but similar peptides have not been characterized in invertebrates. Here the authors show that neuropeptide F functions similar to mammalian incretin in fruit flies, responding to sugar and enhancing insulin-like peptide secretion.

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Autores principales:	Yuto Yoshinari, Hina Kosakamoto, Takumi Kamiyama, Ryo Hoshino, Rena Matsuoka, Shu Kondo, Hiromu Tanimoto, Akira Nakamura, Fumiaki Obata, Ryusuke Niwa
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/b4166c8f5f8449ef8b5ce6a3391e52f3
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spelling	oai:doaj.org-article:b4166c8f5f8449ef8b5ce6a3391e52f32021-12-02T18:50:59ZThe sugar-responsive enteroendocrine neuropeptide F regulates lipid metabolism through glucagon-like and insulin-like hormones in Drosophila melanogaster10.1038/s41467-021-25146-w2041-1723https://doaj.org/article/b4166c8f5f8449ef8b5ce6a3391e52f32021-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-25146-whttps://doaj.org/toc/2041-1723Incretin hormones regulate insulin and glucagon secretion in mammals, but similar peptides have not been characterized in invertebrates. Here the authors show that neuropeptide F functions similar to mammalian incretin in fruit flies, responding to sugar and enhancing insulin-like peptide secretion.Yuto YoshinariHina KosakamotoTakumi KamiyamaRyo HoshinoRena MatsuokaShu KondoHiromu TanimotoAkira NakamuraFumiaki ObataRyusuke NiwaNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-21 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Yuto Yoshinari Hina Kosakamoto Takumi Kamiyama Ryo Hoshino Rena Matsuoka Shu Kondo Hiromu Tanimoto Akira Nakamura Fumiaki Obata Ryusuke Niwa The sugar-responsive enteroendocrine neuropeptide F regulates lipid metabolism through glucagon-like and insulin-like hormones in Drosophila melanogaster
description	Incretin hormones regulate insulin and glucagon secretion in mammals, but similar peptides have not been characterized in invertebrates. Here the authors show that neuropeptide F functions similar to mammalian incretin in fruit flies, responding to sugar and enhancing insulin-like peptide secretion.
format	article
author	Yuto Yoshinari Hina Kosakamoto Takumi Kamiyama Ryo Hoshino Rena Matsuoka Shu Kondo Hiromu Tanimoto Akira Nakamura Fumiaki Obata Ryusuke Niwa
author_facet	Yuto Yoshinari Hina Kosakamoto Takumi Kamiyama Ryo Hoshino Rena Matsuoka Shu Kondo Hiromu Tanimoto Akira Nakamura Fumiaki Obata Ryusuke Niwa
author_sort	Yuto Yoshinari
title	The sugar-responsive enteroendocrine neuropeptide F regulates lipid metabolism through glucagon-like and insulin-like hormones in Drosophila melanogaster
title_short	The sugar-responsive enteroendocrine neuropeptide F regulates lipid metabolism through glucagon-like and insulin-like hormones in Drosophila melanogaster
title_full	The sugar-responsive enteroendocrine neuropeptide F regulates lipid metabolism through glucagon-like and insulin-like hormones in Drosophila melanogaster
title_fullStr	The sugar-responsive enteroendocrine neuropeptide F regulates lipid metabolism through glucagon-like and insulin-like hormones in Drosophila melanogaster
title_full_unstemmed	The sugar-responsive enteroendocrine neuropeptide F regulates lipid metabolism through glucagon-like and insulin-like hormones in Drosophila melanogaster
title_sort	sugar-responsive enteroendocrine neuropeptide f regulates lipid metabolism through glucagon-like and insulin-like hormones in drosophila melanogaster
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/b4166c8f5f8449ef8b5ce6a3391e52f3
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The sugar-responsive enteroendocrine neuropeptide F regulates lipid metabolism through glucagon-like and insulin-like hormones in Drosophila melanogaster

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