Dengue virus activates cGAS through the release of mitochondrial DNA

Dengue virus activates cGAS through the release of mitochondrial DNA

Abstract Cyclic GMP-AMP synthetase (cGAS) is a DNA-specific cytosolic sensor, which detects and initiates host defense responses against microbial DNA. It is thus curious that a recent study identified cGAS as playing important roles in inhibiting positive-sense single-stranded RNA (+ssRNA) viral in...

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Autores principales: Bo Sun, Karin B. Sundström, Jun Jie Chew, Pradeep Bist, Esther S. Gan, Hwee Cheng Tan, Kenneth C. Goh, Tanu Chawla, Choon Kit Tang, Eng Eong Ooi
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/b41daa6c581143b7a27dd423f55e72bf
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