Normal values of nasal NO and exhaled NO in young Chinese people aged 9 â 22 years

Objective: To assess the normal levels of nasal nitric oxide (NNO) and fractional exhaled nitric oxide (FENO) in healthy Chinese young people, and to determine whether the obtained values were associated with age, sex, height, weight, BMI (body mass index) or BSA (body surface area). Methods: One hu...

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Autores principales: Shaohua You, Jing Zhang, Yin Bai, Lingchao Ji, Hongtian Wang
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Lenguaje:EN
Publicado: KeAi Communications Co., Ltd. 2016
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Acceso en línea:https://doaj.org/article/b4277a0324a644b3aa4abe506c3bbcde
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spelling oai:doaj.org-article:b4277a0324a644b3aa4abe506c3bbcde2021-12-02T14:14:28ZNormal values of nasal NO and exhaled NO in young Chinese people aged 9 â 22 years2095-881110.1016/j.wjorl.2016.02.004https://doaj.org/article/b4277a0324a644b3aa4abe506c3bbcde2016-03-01T00:00:00Zhttp://www.sciencedirect.com/science/article/pii/S2095881116000020https://doaj.org/toc/2095-8811Objective: To assess the normal levels of nasal nitric oxide (NNO) and fractional exhaled nitric oxide (FENO) in healthy Chinese young people, and to determine whether the obtained values were associated with age, sex, height, weight, BMI (body mass index) or BSA (body surface area). Methods: One hundred and twenty healthy people were selected from a total of 436 Chinese young people based on their answers to a questionnaire. An electrochemical analyzer (NIOX MINO system) was used to measure NNO and FENO. The relationship between NNO, FENO and age, sex, height, weight, BMI, BSA was analyzed using SPSS software. Results: The values of NNO were normal distributed (mean 273.5 ppb; SD 112.3). The values of FENO were non-normally (Skewed) distributed (median: 14.00 ppb; interquartile range: 7.00 ppb). The obtained NNO values were independent of age, sex, height, weight, BMI and BSA, but were positively correlated to lnFENO (FENO log base e); lnFENO values were also independent of age, height, weight, BMI and BSA, but correlated with NNO and sex. Conclusions: NNO values positively correlate with lnFENO in healthy people and the levels of each may be predicted by the other. The results of this study are expected to serve as a reference for future studies in China. Keywords: Nitric oxide, Nasal cavity, Lower respiratory tract, Normal value, Healthy peopleShaohua YouJing ZhangYin BaiLingchao JiHongtian WangKeAi Communications Co., Ltd.articleOtorhinolaryngologyRF1-547SurgeryRD1-811ENWorld Journal of Otorhinolaryngology-Head and Neck Surgery, Vol 2, Iss 1, Pp 22-27 (2016)
institution DOAJ
collection DOAJ
language EN
topic Otorhinolaryngology
RF1-547
Surgery
RD1-811
spellingShingle Otorhinolaryngology
RF1-547
Surgery
RD1-811
Shaohua You
Jing Zhang
Yin Bai
Lingchao Ji
Hongtian Wang
Normal values of nasal NO and exhaled NO in young Chinese people aged 9 â 22 years
description Objective: To assess the normal levels of nasal nitric oxide (NNO) and fractional exhaled nitric oxide (FENO) in healthy Chinese young people, and to determine whether the obtained values were associated with age, sex, height, weight, BMI (body mass index) or BSA (body surface area). Methods: One hundred and twenty healthy people were selected from a total of 436 Chinese young people based on their answers to a questionnaire. An electrochemical analyzer (NIOX MINO system) was used to measure NNO and FENO. The relationship between NNO, FENO and age, sex, height, weight, BMI, BSA was analyzed using SPSS software. Results: The values of NNO were normal distributed (mean 273.5 ppb; SD 112.3). The values of FENO were non-normally (Skewed) distributed (median: 14.00 ppb; interquartile range: 7.00 ppb). The obtained NNO values were independent of age, sex, height, weight, BMI and BSA, but were positively correlated to lnFENO (FENO log base e); lnFENO values were also independent of age, height, weight, BMI and BSA, but correlated with NNO and sex. Conclusions: NNO values positively correlate with lnFENO in healthy people and the levels of each may be predicted by the other. The results of this study are expected to serve as a reference for future studies in China. Keywords: Nitric oxide, Nasal cavity, Lower respiratory tract, Normal value, Healthy people
format article
author Shaohua You
Jing Zhang
Yin Bai
Lingchao Ji
Hongtian Wang
author_facet Shaohua You
Jing Zhang
Yin Bai
Lingchao Ji
Hongtian Wang
author_sort Shaohua You
title Normal values of nasal NO and exhaled NO in young Chinese people aged 9 â 22 years
title_short Normal values of nasal NO and exhaled NO in young Chinese people aged 9 â 22 years
title_full Normal values of nasal NO and exhaled NO in young Chinese people aged 9 â 22 years
title_fullStr Normal values of nasal NO and exhaled NO in young Chinese people aged 9 â 22 years
title_full_unstemmed Normal values of nasal NO and exhaled NO in young Chinese people aged 9 â 22 years
title_sort normal values of nasal no and exhaled no in young chinese people aged 9 â 22 years
publisher KeAi Communications Co., Ltd.
publishDate 2016
url https://doaj.org/article/b4277a0324a644b3aa4abe506c3bbcde
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AT jingzhang normalvaluesofnasalnoandexhalednoinyoungchinesepeopleaged9a22years
AT yinbai normalvaluesofnasalnoandexhalednoinyoungchinesepeopleaged9a22years
AT lingchaoji normalvaluesofnasalnoandexhalednoinyoungchinesepeopleaged9a22years
AT hongtianwang normalvaluesofnasalnoandexhalednoinyoungchinesepeopleaged9a22years
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