Cyst-Wall-Protein-1 is fundamental for Golgi-like organelle neogenesis and cyst-wall biosynthesis in Giardia lamblia

Giardia lamblia is a human protozoan parasite with two diploid nuclei, which makes complete knock-out of a gene of interest challenging. Here the authors use a Cre/loxP-based approach to knock-out cyst-wall protein 1 (cwp1) and show that CWP1 is essential for cyst-wall biosynthesis.

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Autores principales:	Jacqueline A. Ebneter, Sally D. Heusser, Elisabeth M. Schraner, Adrian B. Hehl, Carmen Faso
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/b428be2fe6974dbb9d80035020385007
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spelling	oai:doaj.org-article:b428be2fe6974dbb9d800350203850072021-12-02T15:35:46ZCyst-Wall-Protein-1 is fundamental for Golgi-like organelle neogenesis and cyst-wall biosynthesis in Giardia lamblia10.1038/ncomms138592041-1723https://doaj.org/article/b428be2fe6974dbb9d800350203850072016-12-01T00:00:00Zhttps://doi.org/10.1038/ncomms13859https://doaj.org/toc/2041-1723Giardia lamblia is a human protozoan parasite with two diploid nuclei, which makes complete knock-out of a gene of interest challenging. Here the authors use a Cre/loxP-based approach to knock-out cyst-wall protein 1 (cwp1) and show that CWP1 is essential for cyst-wall biosynthesis.Jacqueline A. EbneterSally D. HeusserElisabeth M. SchranerAdrian B. HehlCarmen FasoNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-10 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Jacqueline A. Ebneter Sally D. Heusser Elisabeth M. Schraner Adrian B. Hehl Carmen Faso Cyst-Wall-Protein-1 is fundamental for Golgi-like organelle neogenesis and cyst-wall biosynthesis in Giardia lamblia
description	Giardia lamblia is a human protozoan parasite with two diploid nuclei, which makes complete knock-out of a gene of interest challenging. Here the authors use a Cre/loxP-based approach to knock-out cyst-wall protein 1 (cwp1) and show that CWP1 is essential for cyst-wall biosynthesis.
format	article
author	Jacqueline A. Ebneter Sally D. Heusser Elisabeth M. Schraner Adrian B. Hehl Carmen Faso
author_facet	Jacqueline A. Ebneter Sally D. Heusser Elisabeth M. Schraner Adrian B. Hehl Carmen Faso
author_sort	Jacqueline A. Ebneter
title	Cyst-Wall-Protein-1 is fundamental for Golgi-like organelle neogenesis and cyst-wall biosynthesis in Giardia lamblia
title_short	Cyst-Wall-Protein-1 is fundamental for Golgi-like organelle neogenesis and cyst-wall biosynthesis in Giardia lamblia
title_full	Cyst-Wall-Protein-1 is fundamental for Golgi-like organelle neogenesis and cyst-wall biosynthesis in Giardia lamblia
title_fullStr	Cyst-Wall-Protein-1 is fundamental for Golgi-like organelle neogenesis and cyst-wall biosynthesis in Giardia lamblia
title_full_unstemmed	Cyst-Wall-Protein-1 is fundamental for Golgi-like organelle neogenesis and cyst-wall biosynthesis in Giardia lamblia
title_sort	cyst-wall-protein-1 is fundamental for golgi-like organelle neogenesis and cyst-wall biosynthesis in giardia lamblia
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/b428be2fe6974dbb9d80035020385007
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Cyst-Wall-Protein-1 is fundamental for Golgi-like organelle neogenesis and cyst-wall biosynthesis in Giardia lamblia

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