Tailoring the resolution of single-cell RNA sequencing for primary cytotoxic T cells

Tailoring the resolution of single-cell RNA sequencing for primary cytotoxic T cells

Single-cell RNA-seq offers the opportunity to improve efficacy of T-cell based immunotherapy. Here the authors develop a plate-based method for cytotoxic T cell profiling. It captures a higher number of transcripts and detects gene with increased dynamic range in comparison to droplet-based methods.

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Detalles Bibliográficos
Autores principales: Kristiyan Kanev, Patrick Roelli, Ming Wu, Christine Wurmser, Mauro Delorenzi, Michael W. Pfaffl, Dietmar Zehn
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
Science
Q
Acceso en línea:https://doaj.org/article/b42989778967480ba4038ed5f8239c85
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