The origin of GPCRs: identification of mammalian like Rhodopsin, Adhesion, Glutamate and Frizzled GPCRs in fungi.
G protein-coupled receptors (GPCRs) in humans are classified into the five main families named Glutamate, Rhodopsin, Adhesion, Frizzled and Secretin according to the GRAFS classification. Previous results show that these mammalian GRAFS families are well represented in the Metazoan lineages, but the...
Saved in:
Main Authors: | Arunkumar Krishnan, Markus Sällman Almén, Robert Fredriksson, Helgi B Schiöth |
---|---|
Format: | article |
Language: | EN |
Published: |
Public Library of Science (PLoS)
2012
|
Subjects: | |
Online Access: | https://doaj.org/article/b429fdfd6f514a27b6c8519bd97b88d4 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
The dispanins: a novel gene family of ancient origin that contains 14 human members.
by: Markus Sällman Almén, et al.
Published: (2012) -
Super-complexes of adhesion GPCRs and neural guidance receptors
by: Verity A. Jackson, et al.
Published: (2016) -
The Evolutionary History of Vertebrate Adhesion GPCRs and Its Implication on Their Classification
by: Aline Wittlake, et al.
Published: (2021) -
Helix 8 is the essential structural motif of mechanosensitive GPCRs
by: Serap Erdogmus, et al.
Published: (2019) -
The role of kinetic context in apparent biased agonism at GPCRs
by: Carmen Klein Herenbrink, et al.
Published: (2016)