Characterization of clostridium botulinum neurotoxin serotype A (BoNT/A) and fibroblast growth factor receptor interactions using novel receptor dimerization assay
Abstract Clostridium botulinum neurotoxin serotype A (BoNT/A) is a potent neurotoxin that serves as an effective therapeutic for several neuromuscular disorders via induction of temporary muscular paralysis. Specific binding and internalization of BoNT/A into neuronal cells is mediated by its bindin...
Guardado en:
Autores principales: | Nicholas G. James, Shiazah Malik, Bethany J. Sanstrum, Catherine Rhéaume, Ron S. Broide, David M. Jameson, Amy Brideau-Andersen, Birgitte S. Jacky |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2021
|
Materias: | |
Acceso en línea: | https://doaj.org/article/b42c13adfc0c41cca508116cf7c6999f |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Identification of fibroblast growth factor receptor 3 (FGFR3) as a protein receptor for botulinum neurotoxin serotype A (BoNT/A).
por: Birgitte P S Jacky, et al.
Publicado: (2013) -
Analysis of the neurotoxin complex genes in Clostridium botulinum A1-A4 and B1 strains: BoNT/A3, /Ba4 and /B1 clusters are located within plasmids.
por: Theresa J Smith, et al.
Publicado: (2007) -
Clostridium botulinum strain Af84 contains three neurotoxin gene clusters: bont/A2, bont/F4 and bont/F5.
por: Nir Dover, et al.
Publicado: (2013) -
Small-molecule quinolinol inhibitor identified provides protection against BoNT/A in mice.
por: Padma Singh, et al.
Publicado: (2012) -
Recombinant botulinum neurotoxin serotype A1 in vivo characterization
por: Cindy Périer, et al.
Publicado: (2021)