In vivo covalent cross-linking of photon-converted rare-earth nanostructures for tumour localization and theranostics

Directing nanomedicines to desired locations - such as tumour sites - is difficult to achieve selectively. Here, the authors develop a method to covalently crosslink peptide-modified upconversion nanocrystals into tumour sites for photodynamic therapy and show in vivotumour inhibition in mice.

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Autores principales:	Xiangzhao Ai, Chris Jun Hui Ho, Junxin Aw, Amalina Binte Ebrahim Attia, Jing Mu, Yu Wang, Xiaoyong Wang, Yong Wang, Xiaogang Liu, Huabing Chen, Mingyuan Gao, Xiaoyuan Chen, Edwin K.L. Yeow, Gang Liu, Malini Olivo, Bengang Xing
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/b434ee5fcfd84c1696406efcde257735
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spelling	oai:doaj.org-article:b434ee5fcfd84c1696406efcde2577352021-12-02T17:33:21ZIn vivo covalent cross-linking of photon-converted rare-earth nanostructures for tumour localization and theranostics10.1038/ncomms104322041-1723https://doaj.org/article/b434ee5fcfd84c1696406efcde2577352016-01-01T00:00:00Zhttps://doi.org/10.1038/ncomms10432https://doaj.org/toc/2041-1723Directing nanomedicines to desired locations - such as tumour sites - is difficult to achieve selectively. Here, the authors develop a method to covalently crosslink peptide-modified upconversion nanocrystals into tumour sites for photodynamic therapy and show in vivotumour inhibition in mice.Xiangzhao AiChris Jun Hui HoJunxin AwAmalina Binte Ebrahim AttiaJing MuYu WangXiaoyong WangYong WangXiaogang LiuHuabing ChenMingyuan GaoXiaoyuan ChenEdwin K.L. YeowGang LiuMalini OlivoBengang XingNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-9 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Xiangzhao Ai Chris Jun Hui Ho Junxin Aw Amalina Binte Ebrahim Attia Jing Mu Yu Wang Xiaoyong Wang Yong Wang Xiaogang Liu Huabing Chen Mingyuan Gao Xiaoyuan Chen Edwin K.L. Yeow Gang Liu Malini Olivo Bengang Xing In vivo covalent cross-linking of photon-converted rare-earth nanostructures for tumour localization and theranostics
description	Directing nanomedicines to desired locations - such as tumour sites - is difficult to achieve selectively. Here, the authors develop a method to covalently crosslink peptide-modified upconversion nanocrystals into tumour sites for photodynamic therapy and show in vivotumour inhibition in mice.
format	article
author	Xiangzhao Ai Chris Jun Hui Ho Junxin Aw Amalina Binte Ebrahim Attia Jing Mu Yu Wang Xiaoyong Wang Yong Wang Xiaogang Liu Huabing Chen Mingyuan Gao Xiaoyuan Chen Edwin K.L. Yeow Gang Liu Malini Olivo Bengang Xing
author_facet	Xiangzhao Ai Chris Jun Hui Ho Junxin Aw Amalina Binte Ebrahim Attia Jing Mu Yu Wang Xiaoyong Wang Yong Wang Xiaogang Liu Huabing Chen Mingyuan Gao Xiaoyuan Chen Edwin K.L. Yeow Gang Liu Malini Olivo Bengang Xing
author_sort	Xiangzhao Ai
title	In vivo covalent cross-linking of photon-converted rare-earth nanostructures for tumour localization and theranostics
title_short	In vivo covalent cross-linking of photon-converted rare-earth nanostructures for tumour localization and theranostics
title_full	In vivo covalent cross-linking of photon-converted rare-earth nanostructures for tumour localization and theranostics
title_fullStr	In vivo covalent cross-linking of photon-converted rare-earth nanostructures for tumour localization and theranostics
title_full_unstemmed	In vivo covalent cross-linking of photon-converted rare-earth nanostructures for tumour localization and theranostics
title_sort	in vivo covalent cross-linking of photon-converted rare-earth nanostructures for tumour localization and theranostics
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/b434ee5fcfd84c1696406efcde257735
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In vivo covalent cross-linking of photon-converted rare-earth nanostructures for tumour localization and theranostics

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