Control of a programmed cell death pathway in Pseudomonas aeruginosa by an antiterminator

In Pseudomonas aeruginosa, the protein AlpA activates the expression of the alp locus in response to DNA damage, leading to lysis in a subset of cells and enhancing virulence of other, surviving cells. Here, the authors show that AlpA acts as an antiterminator rather than a transcriptional activator...

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Auteurs principaux:	Jennifer M. Peña, Samantha M. Prezioso, Kirsty A. McFarland, Tracy K. Kambara, Kathryn M. Ramsey, Padraig Deighan, Simon L. Dove
Format:	article
Langue:	EN
Publié:	Nature Portfolio 2021
Sujets:	Science Q
Accès en ligne:	https://doaj.org/article/b438ab3975a44616a29582404e1b10c2
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spelling	oai:doaj.org-article:b438ab3975a44616a29582404e1b10c22021-12-02T17:04:52ZControl of a programmed cell death pathway in Pseudomonas aeruginosa by an antiterminator10.1038/s41467-021-21941-72041-1723https://doaj.org/article/b438ab3975a44616a29582404e1b10c22021-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-21941-7https://doaj.org/toc/2041-1723In Pseudomonas aeruginosa, the protein AlpA activates the expression of the alp locus in response to DNA damage, leading to lysis in a subset of cells and enhancing virulence of other, surviving cells. Here, the authors show that AlpA acts as an antiterminator rather than a transcriptional activator.Jennifer M. PeñaSamantha M. PreziosoKirsty A. McFarlandTracy K. KambaraKathryn M. RamseyPadraig DeighanSimon L. DoveNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Jennifer M. Peña Samantha M. Prezioso Kirsty A. McFarland Tracy K. Kambara Kathryn M. Ramsey Padraig Deighan Simon L. Dove Control of a programmed cell death pathway in Pseudomonas aeruginosa by an antiterminator
description	In Pseudomonas aeruginosa, the protein AlpA activates the expression of the alp locus in response to DNA damage, leading to lysis in a subset of cells and enhancing virulence of other, surviving cells. Here, the authors show that AlpA acts as an antiterminator rather than a transcriptional activator.
format	article
author	Jennifer M. Peña Samantha M. Prezioso Kirsty A. McFarland Tracy K. Kambara Kathryn M. Ramsey Padraig Deighan Simon L. Dove
author_facet	Jennifer M. Peña Samantha M. Prezioso Kirsty A. McFarland Tracy K. Kambara Kathryn M. Ramsey Padraig Deighan Simon L. Dove
author_sort	Jennifer M. Peña
title	Control of a programmed cell death pathway in Pseudomonas aeruginosa by an antiterminator
title_short	Control of a programmed cell death pathway in Pseudomonas aeruginosa by an antiterminator
title_full	Control of a programmed cell death pathway in Pseudomonas aeruginosa by an antiterminator
title_fullStr	Control of a programmed cell death pathway in Pseudomonas aeruginosa by an antiterminator
title_full_unstemmed	Control of a programmed cell death pathway in Pseudomonas aeruginosa by an antiterminator
title_sort	control of a programmed cell death pathway in pseudomonas aeruginosa by an antiterminator
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/b438ab3975a44616a29582404e1b10c2
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Control of a programmed cell death pathway in Pseudomonas aeruginosa by an antiterminator

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