Diet-induced adaptive thermogenesis requires neuropeptide FF receptor-2 signalling

Excess caloric intake leads to increased thermogenesis in brown adipose tissue, to limit weight gain. Here, the authors show that neuropeptide FF receptor-2 signalling promotes thermogenesis via control of NPY expression in the arcuate nucleus, and that it absence in mice leads to a failure of activ...

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Autores principales:	Lei Zhang, Chi Kin Ip, I-Chieh J. Lee, Yue Qi, Felicia Reed, Tim Karl, Jac Kee Low, Ronaldo F. Enriquez, Nicola J. Lee, Paul A. Baldock, Herbert Herzog
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/b4414e5490bc452aa201c298f2a70439
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spelling	oai:doaj.org-article:b4414e5490bc452aa201c298f2a704392021-12-02T14:39:08ZDiet-induced adaptive thermogenesis requires neuropeptide FF receptor-2 signalling10.1038/s41467-018-06462-02041-1723https://doaj.org/article/b4414e5490bc452aa201c298f2a704392018-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-06462-0https://doaj.org/toc/2041-1723Excess caloric intake leads to increased thermogenesis in brown adipose tissue, to limit weight gain. Here, the authors show that neuropeptide FF receptor-2 signalling promotes thermogenesis via control of NPY expression in the arcuate nucleus, and that it absence in mice leads to a failure of activation of diet-induced thermogenesis and the development of exacerbated obesity.Lei ZhangChi Kin IpI-Chieh J. LeeYue QiFelicia ReedTim KarlJac Kee LowRonaldo F. EnriquezNicola J. LeePaul A. BaldockHerbert HerzogNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-19 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Lei Zhang Chi Kin Ip I-Chieh J. Lee Yue Qi Felicia Reed Tim Karl Jac Kee Low Ronaldo F. Enriquez Nicola J. Lee Paul A. Baldock Herbert Herzog Diet-induced adaptive thermogenesis requires neuropeptide FF receptor-2 signalling
description	Excess caloric intake leads to increased thermogenesis in brown adipose tissue, to limit weight gain. Here, the authors show that neuropeptide FF receptor-2 signalling promotes thermogenesis via control of NPY expression in the arcuate nucleus, and that it absence in mice leads to a failure of activation of diet-induced thermogenesis and the development of exacerbated obesity.
format	article
author	Lei Zhang Chi Kin Ip I-Chieh J. Lee Yue Qi Felicia Reed Tim Karl Jac Kee Low Ronaldo F. Enriquez Nicola J. Lee Paul A. Baldock Herbert Herzog
author_facet	Lei Zhang Chi Kin Ip I-Chieh J. Lee Yue Qi Felicia Reed Tim Karl Jac Kee Low Ronaldo F. Enriquez Nicola J. Lee Paul A. Baldock Herbert Herzog
author_sort	Lei Zhang
title	Diet-induced adaptive thermogenesis requires neuropeptide FF receptor-2 signalling
title_short	Diet-induced adaptive thermogenesis requires neuropeptide FF receptor-2 signalling
title_full	Diet-induced adaptive thermogenesis requires neuropeptide FF receptor-2 signalling
title_fullStr	Diet-induced adaptive thermogenesis requires neuropeptide FF receptor-2 signalling
title_full_unstemmed	Diet-induced adaptive thermogenesis requires neuropeptide FF receptor-2 signalling
title_sort	diet-induced adaptive thermogenesis requires neuropeptide ff receptor-2 signalling
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/b4414e5490bc452aa201c298f2a70439
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Diet-induced adaptive thermogenesis requires neuropeptide FF receptor-2 signalling

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