Physiological and metabolomic consequences of reduced expression of the Drosophila brummer triglyceride Lipase.

Physiological and metabolomic consequences of reduced expression of the Drosophila brummer triglyceride Lipase.

Disruption of lipolysis has widespread effects on intermediary metabolism and organismal phenotypes. Defects in lipolysis can be modeled in Drosophila melanogaster through genetic manipulations of brummer (bmm), which encodes a triglyceride lipase orthologous to mammalian Adipose Triglyceride Lipase...

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Autores principales: Nestor O Nazario-Yepiz, Jaime Fernández Sobaberas, Roberta Lyman, Marion R Campbell, Vijay Shankar, Robert R H Anholt, Trudy F C Mackay
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2021
Materias:
Medicine
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Science
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Acceso en línea:https://doaj.org/article/b451a74a50774c0fb3146510816e9adc
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