Insulin receptor substrate 1 gene expression is strongly up-regulated by HSPB8 silencing in U87 glioma cells

Objective. The aim of the present investigation was to study the expression of genes encoding IRS1 (insulin receptor substrate 1) and some other functionally active proteins in U87 glioma cells under silencing of polyfunctional chaperone HSPB8 for evaluation of the possible significance of this prot...

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Autores principales: Hnatiuk Oksana S., Tsymbal Dariia O., Minchenko Dmytro O., Khita Olena O., Viletska Yulia M., Rundytska Olha V., Kozynkevych Halyna E., Maslak Hanna S., Minchenko Oleksandr H.
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Publicado: Sciendo 2020
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Acceso en línea:https://doaj.org/article/b45330ce0084424193b26340eb8116c3
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spelling oai:doaj.org-article:b45330ce0084424193b26340eb8116c32021-12-02T17:49:33ZInsulin receptor substrate 1 gene expression is strongly up-regulated by HSPB8 silencing in U87 glioma cells1336-032910.2478/enr-2020-0026https://doaj.org/article/b45330ce0084424193b26340eb8116c32020-10-01T00:00:00Zhttps://doi.org/10.2478/enr-2020-0026https://doaj.org/toc/1336-0329Objective. The aim of the present investigation was to study the expression of genes encoding IRS1 (insulin receptor substrate 1) and some other functionally active proteins in U87 glioma cells under silencing of polyfunctional chaperone HSPB8 for evaluation of the possible significance of this protein in intergenic interactions.Hnatiuk Oksana S.Tsymbal Dariia O.Minchenko Dmytro O.Khita Olena O.Viletska Yulia M.Rundytska Olha V.Kozynkevych Halyna E.Maslak Hanna S.Minchenko Oleksandr H.Sciendoarticlesilencing hspb8mrna expressionirs1homer3perpclo1myl9per2gadd45au87 glioma cellsDiseases of the endocrine glands. Clinical endocrinologyRC648-665ENEndocrine Regulations, Vol 54, Iss 4, Pp 231-243 (2020)
institution DOAJ
collection DOAJ
language EN
topic silencing hspb8
mrna expression
irs1
homer3
perp
clo1
myl9
per2
gadd45a
u87 glioma cells
Diseases of the endocrine glands. Clinical endocrinology
RC648-665
spellingShingle silencing hspb8
mrna expression
irs1
homer3
perp
clo1
myl9
per2
gadd45a
u87 glioma cells
Diseases of the endocrine glands. Clinical endocrinology
RC648-665
Hnatiuk Oksana S.
Tsymbal Dariia O.
Minchenko Dmytro O.
Khita Olena O.
Viletska Yulia M.
Rundytska Olha V.
Kozynkevych Halyna E.
Maslak Hanna S.
Minchenko Oleksandr H.
Insulin receptor substrate 1 gene expression is strongly up-regulated by HSPB8 silencing in U87 glioma cells
description Objective. The aim of the present investigation was to study the expression of genes encoding IRS1 (insulin receptor substrate 1) and some other functionally active proteins in U87 glioma cells under silencing of polyfunctional chaperone HSPB8 for evaluation of the possible significance of this protein in intergenic interactions.
format article
author Hnatiuk Oksana S.
Tsymbal Dariia O.
Minchenko Dmytro O.
Khita Olena O.
Viletska Yulia M.
Rundytska Olha V.
Kozynkevych Halyna E.
Maslak Hanna S.
Minchenko Oleksandr H.
author_facet Hnatiuk Oksana S.
Tsymbal Dariia O.
Minchenko Dmytro O.
Khita Olena O.
Viletska Yulia M.
Rundytska Olha V.
Kozynkevych Halyna E.
Maslak Hanna S.
Minchenko Oleksandr H.
author_sort Hnatiuk Oksana S.
title Insulin receptor substrate 1 gene expression is strongly up-regulated by HSPB8 silencing in U87 glioma cells
title_short Insulin receptor substrate 1 gene expression is strongly up-regulated by HSPB8 silencing in U87 glioma cells
title_full Insulin receptor substrate 1 gene expression is strongly up-regulated by HSPB8 silencing in U87 glioma cells
title_fullStr Insulin receptor substrate 1 gene expression is strongly up-regulated by HSPB8 silencing in U87 glioma cells
title_full_unstemmed Insulin receptor substrate 1 gene expression is strongly up-regulated by HSPB8 silencing in U87 glioma cells
title_sort insulin receptor substrate 1 gene expression is strongly up-regulated by hspb8 silencing in u87 glioma cells
publisher Sciendo
publishDate 2020
url https://doaj.org/article/b45330ce0084424193b26340eb8116c3
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