Insulin receptor substrate 1 gene expression is strongly up-regulated by HSPB8 silencing in U87 glioma cells
Objective. The aim of the present investigation was to study the expression of genes encoding IRS1 (insulin receptor substrate 1) and some other functionally active proteins in U87 glioma cells under silencing of polyfunctional chaperone HSPB8 for evaluation of the possible significance of this prot...
Guardado en:
Autores principales: | , , , , , , , , |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Sciendo
2020
|
Materias: | |
Acceso en línea: | https://doaj.org/article/b45330ce0084424193b26340eb8116c3 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
id |
oai:doaj.org-article:b45330ce0084424193b26340eb8116c3 |
---|---|
record_format |
dspace |
spelling |
oai:doaj.org-article:b45330ce0084424193b26340eb8116c32021-12-02T17:49:33ZInsulin receptor substrate 1 gene expression is strongly up-regulated by HSPB8 silencing in U87 glioma cells1336-032910.2478/enr-2020-0026https://doaj.org/article/b45330ce0084424193b26340eb8116c32020-10-01T00:00:00Zhttps://doi.org/10.2478/enr-2020-0026https://doaj.org/toc/1336-0329Objective. The aim of the present investigation was to study the expression of genes encoding IRS1 (insulin receptor substrate 1) and some other functionally active proteins in U87 glioma cells under silencing of polyfunctional chaperone HSPB8 for evaluation of the possible significance of this protein in intergenic interactions.Hnatiuk Oksana S.Tsymbal Dariia O.Minchenko Dmytro O.Khita Olena O.Viletska Yulia M.Rundytska Olha V.Kozynkevych Halyna E.Maslak Hanna S.Minchenko Oleksandr H.Sciendoarticlesilencing hspb8mrna expressionirs1homer3perpclo1myl9per2gadd45au87 glioma cellsDiseases of the endocrine glands. Clinical endocrinologyRC648-665ENEndocrine Regulations, Vol 54, Iss 4, Pp 231-243 (2020) |
institution |
DOAJ |
collection |
DOAJ |
language |
EN |
topic |
silencing hspb8 mrna expression irs1 homer3 perp clo1 myl9 per2 gadd45a u87 glioma cells Diseases of the endocrine glands. Clinical endocrinology RC648-665 |
spellingShingle |
silencing hspb8 mrna expression irs1 homer3 perp clo1 myl9 per2 gadd45a u87 glioma cells Diseases of the endocrine glands. Clinical endocrinology RC648-665 Hnatiuk Oksana S. Tsymbal Dariia O. Minchenko Dmytro O. Khita Olena O. Viletska Yulia M. Rundytska Olha V. Kozynkevych Halyna E. Maslak Hanna S. Minchenko Oleksandr H. Insulin receptor substrate 1 gene expression is strongly up-regulated by HSPB8 silencing in U87 glioma cells |
description |
Objective. The aim of the present investigation was to study the expression of genes encoding IRS1 (insulin receptor substrate 1) and some other functionally active proteins in U87 glioma cells under silencing of polyfunctional chaperone HSPB8 for evaluation of the possible significance of this protein in intergenic interactions. |
format |
article |
author |
Hnatiuk Oksana S. Tsymbal Dariia O. Minchenko Dmytro O. Khita Olena O. Viletska Yulia M. Rundytska Olha V. Kozynkevych Halyna E. Maslak Hanna S. Minchenko Oleksandr H. |
author_facet |
Hnatiuk Oksana S. Tsymbal Dariia O. Minchenko Dmytro O. Khita Olena O. Viletska Yulia M. Rundytska Olha V. Kozynkevych Halyna E. Maslak Hanna S. Minchenko Oleksandr H. |
author_sort |
Hnatiuk Oksana S. |
title |
Insulin receptor substrate 1 gene expression is strongly up-regulated by HSPB8 silencing in U87 glioma cells |
title_short |
Insulin receptor substrate 1 gene expression is strongly up-regulated by HSPB8 silencing in U87 glioma cells |
title_full |
Insulin receptor substrate 1 gene expression is strongly up-regulated by HSPB8 silencing in U87 glioma cells |
title_fullStr |
Insulin receptor substrate 1 gene expression is strongly up-regulated by HSPB8 silencing in U87 glioma cells |
title_full_unstemmed |
Insulin receptor substrate 1 gene expression is strongly up-regulated by HSPB8 silencing in U87 glioma cells |
title_sort |
insulin receptor substrate 1 gene expression is strongly up-regulated by hspb8 silencing in u87 glioma cells |
publisher |
Sciendo |
publishDate |
2020 |
url |
https://doaj.org/article/b45330ce0084424193b26340eb8116c3 |
work_keys_str_mv |
AT hnatiukoksanas insulinreceptorsubstrate1geneexpressionisstronglyupregulatedbyhspb8silencinginu87gliomacells AT tsymbaldariiao insulinreceptorsubstrate1geneexpressionisstronglyupregulatedbyhspb8silencinginu87gliomacells AT minchenkodmytroo insulinreceptorsubstrate1geneexpressionisstronglyupregulatedbyhspb8silencinginu87gliomacells AT khitaolenao insulinreceptorsubstrate1geneexpressionisstronglyupregulatedbyhspb8silencinginu87gliomacells AT viletskayuliam insulinreceptorsubstrate1geneexpressionisstronglyupregulatedbyhspb8silencinginu87gliomacells AT rundytskaolhav insulinreceptorsubstrate1geneexpressionisstronglyupregulatedbyhspb8silencinginu87gliomacells AT kozynkevychhalynae insulinreceptorsubstrate1geneexpressionisstronglyupregulatedbyhspb8silencinginu87gliomacells AT maslakhannas insulinreceptorsubstrate1geneexpressionisstronglyupregulatedbyhspb8silencinginu87gliomacells AT minchenkooleksandrh insulinreceptorsubstrate1geneexpressionisstronglyupregulatedbyhspb8silencinginu87gliomacells |
_version_ |
1718379429123588096 |