Oral and colonic microbiomes and colon cancer

Oral microbiota include bacteria, fungi, protozoa, and viruses, which can translocate via the digestive tract and may favor local benign or malignant pathology development. Some researchers have studied the physiopathological mechanisms involving the role of oral microorganisms in intestinal disease...

Full description

Saved in:

Bibliographic Details
Main Authors:	Vitorino dos Santos, Lister dos Santos
Format:	article
Language:	EN
Published:	Shiraz University of Medical Sciences 2021
Subjects:	colorectal cancer dysbiosis microbiota mycobiota Medicine R
Online Access:	https://doaj.org/article/b454992830c840528ffd94e23d5b52a5
Tags:	Add Tag No Tags, Be the first to tag this record!

id	oai:doaj.org-article:b454992830c840528ffd94e23d5b52a5
record_format	dspace
spelling	oai:doaj.org-article:b454992830c840528ffd94e23d5b52a52021-11-14T06:50:56ZOral and colonic microbiomes and colon cancer2783-243010.30476/acrr.2021.92511.1112https://doaj.org/article/b454992830c840528ffd94e23d5b52a52021-09-01T00:00:00Zhttps://colorectalresearch.sums.ac.ir/article_47801_fac02e8f88eb782dd5b2db9bfd632873.pdfhttps://doaj.org/toc/2783-2430Oral microbiota include bacteria, fungi, protozoa, and viruses, which can translocate via the digestive tract and may favor local benign or malignant pathology development. Some researchers have studied the physiopathological mechanisms involving the role of oral microorganisms in intestinal diseases. Two significant areas of these studies are colorectal cancer and coronavirus disease 2019 (COVID-19). Some of the intestinal manifestations of this pandemic may be associated with dysbiosis. Both synergistic and antagonistic bacterial and fungal associations have been described in patients with colorectal cancer, characterizing dysbiosis. Oral microbes can cause opposing effects to the beneficial intestinal flora, eliciting DNA epithelial damage and apoptosis in the bowel as tumor triggering factors. Increased levels of Fusobacterium nucleatum and Porphyromonas gingivalis have been found in association with colorectal cancer. The recent advent of new biomarkers to diagnose colorectal tumors is also considered. The aim of these comments is to emphasize the usefulness of the more recent findings.Vitorino dos SantosLister dos SantosShiraz University of Medical Sciencesarticlecolorectal cancerdysbiosismicrobiotamycobiotaMedicineRENIranian Journal of Colorectal Research, Vol 9, Iss 3, Pp 122-123 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	colorectal cancer dysbiosis microbiota mycobiota Medicine R
spellingShingle	colorectal cancer dysbiosis microbiota mycobiota Medicine R Vitorino dos Santos Lister dos Santos Oral and colonic microbiomes and colon cancer
description	Oral microbiota include bacteria, fungi, protozoa, and viruses, which can translocate via the digestive tract and may favor local benign or malignant pathology development. Some researchers have studied the physiopathological mechanisms involving the role of oral microorganisms in intestinal diseases. Two significant areas of these studies are colorectal cancer and coronavirus disease 2019 (COVID-19). Some of the intestinal manifestations of this pandemic may be associated with dysbiosis. Both synergistic and antagonistic bacterial and fungal associations have been described in patients with colorectal cancer, characterizing dysbiosis. Oral microbes can cause opposing effects to the beneficial intestinal flora, eliciting DNA epithelial damage and apoptosis in the bowel as tumor triggering factors. Increased levels of Fusobacterium nucleatum and Porphyromonas gingivalis have been found in association with colorectal cancer. The recent advent of new biomarkers to diagnose colorectal tumors is also considered. The aim of these comments is to emphasize the usefulness of the more recent findings.
format	article
author	Vitorino dos Santos Lister dos Santos
author_facet	Vitorino dos Santos Lister dos Santos
author_sort	Vitorino dos Santos
title	Oral and colonic microbiomes and colon cancer
title_short	Oral and colonic microbiomes and colon cancer
title_full	Oral and colonic microbiomes and colon cancer
title_fullStr	Oral and colonic microbiomes and colon cancer
title_full_unstemmed	Oral and colonic microbiomes and colon cancer
title_sort	oral and colonic microbiomes and colon cancer
publisher	Shiraz University of Medical Sciences
publishDate	2021
url	https://doaj.org/article/b454992830c840528ffd94e23d5b52a5
work_keys_str_mv	AT vitorinodossantos oralandcolonicmicrobiomesandcoloncancer AT listerdossantos oralandcolonicmicrobiomesandcoloncancer
_version_	1718429860839292928

Oral and colonic microbiomes and colon cancer

Similar Items