Maternal and Neonatal Outcomes Resulting from Antepartum Hemorrhage in Women with Placenta Previa and Its Associated Risk Factors: A Single-Center Retrospective Study

Shu-Yu Long, Qiong Yang, Rui Chi, Li Luo, Xi Xiong, Zheng-Qiong Chen Department of Obstetrics and Gynecology, The Second Affiliated Hospital of Army Medical University, Chongqing 400037, People’s Republic of ChinaCorrespondence: Zheng-Qiong Chen Email chenzhengqiong75@163.comPurpose: Antep...

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Autores principales:	Long SY, Yang Q, Chi R, Luo L, Xiong X, Chen ZQ
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2021
Materias:	placenta previa antepartum hemorrhage bleeding pregnancy complications risk factor Therapeutics. Pharmacology RM1-950
Acceso en línea:	https://doaj.org/article/b4588627838d4799a9425b59555abe01
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spelling	oai:doaj.org-article:b4588627838d4799a9425b59555abe012021-12-02T15:13:39ZMaternal and Neonatal Outcomes Resulting from Antepartum Hemorrhage in Women with Placenta Previa and Its Associated Risk Factors: A Single-Center Retrospective Study1178-203Xhttps://doaj.org/article/b4588627838d4799a9425b59555abe012021-01-01T00:00:00Zhttps://www.dovepress.com/maternal-and-neonatal-outcomes-resulting-from-antepartum-hemorrhage-in-peer-reviewed-article-TCRMhttps://doaj.org/toc/1178-203XShu-Yu Long, Qiong Yang, Rui Chi, Li Luo, Xi Xiong, Zheng-Qiong Chen Department of Obstetrics and Gynecology, The Second Affiliated Hospital of Army Medical University, Chongqing 400037, People’s Republic of ChinaCorrespondence: Zheng-Qiong Chen Email chenzhengqiong75@163.comPurpose: Antepartum hemorrhage (APH) in women with placenta previa (PP) has been associated with increased perinatal complications. The present study aims to evaluate the maternal and neonatal outcomes, and risk factors related to this condition.Methods: This retrospective study was conducted in the Obstetrics and Gynecology Department of the Second Affiliated Hospital of Army Military Medical University from January 2016 to September 2019, which included all women with PP. The clinical and ultrasound features in patients with or without APH were compared.Results: There were 233 women with APH and 302 women without APH in the cohort. Most of the women with APH were prone to adverse maternal and neonatal outcomes. In the logistic regression analysis, cervical length was inversely correlated to APH (OR: 0.972, 95% CI: 0.952&sim; 0.993), while complete PP increased the risk for APH (OR: 2.121, 95% CI: 1.208&sim; 3.732). Furthermore, the anterior placenta increased the risk for APH (OR: 1.664, 95% CI: 1.139&sim; 2.430), the partial absence of the over lying myometrium increased the risk for APH (OR: 2.015, 95% CI: 1.293&sim; 3.141), and the previous history of uterine artery embolization (UAE) increased the highest risk for APH (OR: 11.706, 95% CI: 1.424&sim; 96.195).Conclusion: Obstetricians should be aware of the increased risk of adverse pregnancy outcomes related to APH in women with complete PP, short cervical length, anterior placenta, and partially absent over lying myometrium. Prior UAE is a novel risk factor associated with increased prevalence of APH.Keywords: placenta previa, antepartum hemorrhage, bleeding, pregnancy complications, risk factorLong SYYang QChi RLuo LXiong XChen ZQDove Medical Pressarticleplacenta previaantepartum hemorrhagebleedingpregnancy complicationsrisk factorTherapeutics. PharmacologyRM1-950ENTherapeutics and Clinical Risk Management, Vol Volume 17, Pp 31-38 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	placenta previa antepartum hemorrhage bleeding pregnancy complications risk factor Therapeutics. Pharmacology RM1-950
spellingShingle	placenta previa antepartum hemorrhage bleeding pregnancy complications risk factor Therapeutics. Pharmacology RM1-950 Long SY Yang Q Chi R Luo L Xiong X Chen ZQ Maternal and Neonatal Outcomes Resulting from Antepartum Hemorrhage in Women with Placenta Previa and Its Associated Risk Factors: A Single-Center Retrospective Study
description	Shu-Yu Long, Qiong Yang, Rui Chi, Li Luo, Xi Xiong, Zheng-Qiong Chen Department of Obstetrics and Gynecology, The Second Affiliated Hospital of Army Medical University, Chongqing 400037, People’s Republic of ChinaCorrespondence: Zheng-Qiong Chen Email chenzhengqiong75@163.comPurpose: Antepartum hemorrhage (APH) in women with placenta previa (PP) has been associated with increased perinatal complications. The present study aims to evaluate the maternal and neonatal outcomes, and risk factors related to this condition.Methods: This retrospective study was conducted in the Obstetrics and Gynecology Department of the Second Affiliated Hospital of Army Military Medical University from January 2016 to September 2019, which included all women with PP. The clinical and ultrasound features in patients with or without APH were compared.Results: There were 233 women with APH and 302 women without APH in the cohort. Most of the women with APH were prone to adverse maternal and neonatal outcomes. In the logistic regression analysis, cervical length was inversely correlated to APH (OR: 0.972, 95% CI: 0.952&sim; 0.993), while complete PP increased the risk for APH (OR: 2.121, 95% CI: 1.208&sim; 3.732). Furthermore, the anterior placenta increased the risk for APH (OR: 1.664, 95% CI: 1.139&sim; 2.430), the partial absence of the over lying myometrium increased the risk for APH (OR: 2.015, 95% CI: 1.293&sim; 3.141), and the previous history of uterine artery embolization (UAE) increased the highest risk for APH (OR: 11.706, 95% CI: 1.424&sim; 96.195).Conclusion: Obstetricians should be aware of the increased risk of adverse pregnancy outcomes related to APH in women with complete PP, short cervical length, anterior placenta, and partially absent over lying myometrium. Prior UAE is a novel risk factor associated with increased prevalence of APH.Keywords: placenta previa, antepartum hemorrhage, bleeding, pregnancy complications, risk factor
format	article
author	Long SY Yang Q Chi R Luo L Xiong X Chen ZQ
author_facet	Long SY Yang Q Chi R Luo L Xiong X Chen ZQ
author_sort	Long SY
title	Maternal and Neonatal Outcomes Resulting from Antepartum Hemorrhage in Women with Placenta Previa and Its Associated Risk Factors: A Single-Center Retrospective Study
title_short	Maternal and Neonatal Outcomes Resulting from Antepartum Hemorrhage in Women with Placenta Previa and Its Associated Risk Factors: A Single-Center Retrospective Study
title_full	Maternal and Neonatal Outcomes Resulting from Antepartum Hemorrhage in Women with Placenta Previa and Its Associated Risk Factors: A Single-Center Retrospective Study
title_fullStr	Maternal and Neonatal Outcomes Resulting from Antepartum Hemorrhage in Women with Placenta Previa and Its Associated Risk Factors: A Single-Center Retrospective Study
title_full_unstemmed	Maternal and Neonatal Outcomes Resulting from Antepartum Hemorrhage in Women with Placenta Previa and Its Associated Risk Factors: A Single-Center Retrospective Study
title_sort	maternal and neonatal outcomes resulting from antepartum hemorrhage in women with placenta previa and its associated risk factors: a single-center retrospective study
publisher	Dove Medical Press
publishDate	2021
url	https://doaj.org/article/b4588627838d4799a9425b59555abe01
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Maternal and Neonatal Outcomes Resulting from Antepartum Hemorrhage in Women with Placenta Previa and Its Associated Risk Factors: A Single-Center Retrospective Study

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