Association of CLDN18 Protein Expression with Clinicopathological Features and Prognosis in Advanced Gastric and Gastroesophageal Junction Adenocarcinomas

Association of CLDN18 Protein Expression with Clinicopathological Features and Prognosis in Advanced Gastric and Gastroesophageal Junction Adenocarcinomas

The tight junction protein claudin-18 (CLDN18), is often expressed in various cancer types including gastric (GC) and gastroesophageal adenocarcinomas (GECs). In the last years, the isoform CLDN18.2 emerged as a potential drug target in metastatic GCs, leading to the development of monoclonal antibo...

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Main Authors: Antonio Pellino, Stefano Brignola, Erika Riello, Monia Niero, Sabina Murgioni, Maria Guido, Floriana Nappo, Gianluca Businello, Marta Sbaraglia, Francesca Bergamo, Gaya Spolverato, Salvatore Pucciarelli, Stefano Merigliano, Pierluigi Pilati, Francesco Cavallin, Stefano Realdon, Fabio Farinati, Angelo Paolo Dei Tos, Vittorina Zagonel, Sara Lonardi, Fotios Loupakis, Matteo Fassan
Format: article
Language:EN
Published: MDPI AG 2021
Subjects:
CLDN18.2
gastric adenocarcinoma
biomarkers
immunohistochemistry
Medicine
R
Online Access:https://doaj.org/article/b46fe1fae9344ce2b6b50d9f95f3903c
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https://doaj.org/article/b46fe1fae9344ce2b6b50d9f95f3903c

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