Endovascular progenitors infiltrate melanomas and differentiate towards a variety of vascular beds promoting tumor metastasis
The contribution of endothelial progenitor cells to tumor angiogenesis is controversial. Here, the authors trace the lineage differentiation of endovascular progenitor cells and demonstrate their functional importance in tumor vascularization and progression.
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Main Authors: | Prudence Donovan, Jatin Patel, James Dight, Ho Yi Wong, Seen-Ling Sim, Valentine Murigneux, Mathias Francois, Kiarash Khosrotehrani |
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Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2019
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Subjects: | |
Online Access: | https://doaj.org/article/b472c48355de4681b6ea5ebc4841da96 |
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