Experience of application the 99mTc-MIBI scintigraphy for preoperative visualization of parathyroid glands in patients with gyperparathyrosis

Aim. The aim of our study was to explore the possibilities of scintigraphy with 99mTc-MIBI for diagnosis of parathyroid glands disorders and advantages of SPECT/CT technology with 99mTc-MIBI for ectopic glands. Material and Methods. The study involved 682 patients with parathyroid glands disorder...

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Autores principales:	I.V. Noverko, V.Yu. Kundin, M.V. Satyr, A.Ye. Kovalenko, M.Yu. Bolgov, B.B. Guda, P.P. Zunych
Formato:	article
Lenguaje:	EN UK
Publicado:	Danylo Halytsky Lviv National Medical University 2019
Materias:	hyperparathyrosis, parathyroid glands, scintigraphy, spect/ct, 99mtc-mibi Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/b4741f53ab47475093a715419e9ad697
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spelling	oai:doaj.org-article:b4741f53ab47475093a715419e9ad6972021-11-10T19:49:51ZExperience of application the 99mTc-MIBI scintigraphy for preoperative visualization of parathyroid glands in patients with gyperparathyrosis1029-42442415-330310.25040/aml2019.02.058https://doaj.org/article/b4741f53ab47475093a715419e9ad6972019-09-01T00:00:00Zhttps://amljournal.com/index.php/journal/article/view/62https://doaj.org/toc/1029-4244https://doaj.org/toc/2415-3303Aim. The aim of our study was to explore the possibilities of scintigraphy with 99mTc-MIBI for diagnosis of parathyroid glands disorders and advantages of SPECT/CT technology with 99mTc-MIBI for ectopic glands. Material and Methods. The study involved 682 patients with parathyroid glands disorders. 619 (90.8%) of them were women, 63 (9.2%) - men. With primary hyperparathyroidism were examined 549 (80.5%) patients, with secondary/tertiary hyperparathyroidism - 133 (19.5%) patients. Results and Discussion. In 490 patients (71.9%) high-quality diagnostic images were obtained. In 50 of them (7.3% patients) the multiglandular disease was visualized. In 52 (7.6%) patients were detected the intrathyroid adenomas of the parathyroid glands or parathyroid adenomas, which bordered directly with the thyroid tissue along the posterior surface of the thyroid gland. In 26 (3.8%) patients parathyroid adenomas were localized in the upper, anterior and/or middle mediastinum. Negative results of scintigraphy occurred in 114 (16.7%) patients. Conclusions. Results of study demonstrate high diagnostic value of scintigraphy with 99mTc-MIBI in diagnosis parathyroid glands disorders; SPECT/CT with 99mTc-MIBI allows more precisely determine the localization of ectopic parathyroid glands.I.V. NoverkoV.Yu. KundinM.V. SatyrA.Ye. KovalenkoM.Yu. BolgovB.B. GudaP.P. ZunychDanylo Halytsky Lviv National Medical Universityarticlehyperparathyrosis, parathyroid glands, scintigraphy, spect/ct, 99mtc-mibiMedicine (General)R5-920ENUKActa Medica Leopoliensia, Vol 25, Iss 2-3, Pp 58-63 (2019)
institution	DOAJ
collection	DOAJ
language	EN UK
topic	hyperparathyrosis, parathyroid glands, scintigraphy, spect/ct, 99mtc-mibi Medicine (General) R5-920
spellingShingle	hyperparathyrosis, parathyroid glands, scintigraphy, spect/ct, 99mtc-mibi Medicine (General) R5-920 I.V. Noverko V.Yu. Kundin M.V. Satyr A.Ye. Kovalenko M.Yu. Bolgov B.B. Guda P.P. Zunych Experience of application the 99mTc-MIBI scintigraphy for preoperative visualization of parathyroid glands in patients with gyperparathyrosis
description	Aim. The aim of our study was to explore the possibilities of scintigraphy with 99mTc-MIBI for diagnosis of parathyroid glands disorders and advantages of SPECT/CT technology with 99mTc-MIBI for ectopic glands. Material and Methods. The study involved 682 patients with parathyroid glands disorders. 619 (90.8%) of them were women, 63 (9.2%) - men. With primary hyperparathyroidism were examined 549 (80.5%) patients, with secondary/tertiary hyperparathyroidism - 133 (19.5%) patients. Results and Discussion. In 490 patients (71.9%) high-quality diagnostic images were obtained. In 50 of them (7.3% patients) the multiglandular disease was visualized. In 52 (7.6%) patients were detected the intrathyroid adenomas of the parathyroid glands or parathyroid adenomas, which bordered directly with the thyroid tissue along the posterior surface of the thyroid gland. In 26 (3.8%) patients parathyroid adenomas were localized in the upper, anterior and/or middle mediastinum. Negative results of scintigraphy occurred in 114 (16.7%) patients. Conclusions. Results of study demonstrate high diagnostic value of scintigraphy with 99mTc-MIBI in diagnosis parathyroid glands disorders; SPECT/CT with 99mTc-MIBI allows more precisely determine the localization of ectopic parathyroid glands.
format	article
author	I.V. Noverko V.Yu. Kundin M.V. Satyr A.Ye. Kovalenko M.Yu. Bolgov B.B. Guda P.P. Zunych
author_facet	I.V. Noverko V.Yu. Kundin M.V. Satyr A.Ye. Kovalenko M.Yu. Bolgov B.B. Guda P.P. Zunych
author_sort	I.V. Noverko
title	Experience of application the 99mTc-MIBI scintigraphy for preoperative visualization of parathyroid glands in patients with gyperparathyrosis
title_short	Experience of application the 99mTc-MIBI scintigraphy for preoperative visualization of parathyroid glands in patients with gyperparathyrosis
title_full	Experience of application the 99mTc-MIBI scintigraphy for preoperative visualization of parathyroid glands in patients with gyperparathyrosis
title_fullStr	Experience of application the 99mTc-MIBI scintigraphy for preoperative visualization of parathyroid glands in patients with gyperparathyrosis
title_full_unstemmed	Experience of application the 99mTc-MIBI scintigraphy for preoperative visualization of parathyroid glands in patients with gyperparathyrosis
title_sort	experience of application the 99mtc-mibi scintigraphy for preoperative visualization of parathyroid glands in patients with gyperparathyrosis
publisher	Danylo Halytsky Lviv National Medical University
publishDate	2019
url	https://doaj.org/article/b4741f53ab47475093a715419e9ad697
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Experience of application the 99mTc-MIBI scintigraphy for preoperative visualization of parathyroid glands in patients with gyperparathyrosis

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