Genomic heterogeneity of multiple synchronous lung cancer

Genomic heterogeneity of multiple synchronous lung cancer

Some patients present with multiple lung tumours but it is unclear whether these are metastases or individual lesions. Here, the authors use genomics techniques to demonstrate in six patients that multiple tumours have individual genetic profiles and represent separate tumours.

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Detalles Bibliográficos
Autores principales: Yu Liu, Jianjun Zhang, Lin Li, Guangliang Yin, Jianhua Zhang, Shan Zheng, Hannah Cheung, Ning Wu, Ning Lu, Xizeng Mao, Longhai Yang, Jiexin Zhang, Li Zhang, Sahil Seth, Huang Chen, Xingzhi Song, Kan Liu, Yongqiang Xie, Lina Zhou, Chuanduo Zhao, Naijun Han, Wenting Chen, Susu Zhang, Longyun Chen, Wenjun Cai, Miaozhong Shen, Ningzhi Xu, Shujun Cheng, Huanming Yang, J. Jack Lee, Arlene Correa, Junya Fujimoto, Carmen Behrens, Chi-Wan Chow, William N. William, John V. Heymach, Waun Ki Hong, Stephen Swisher, Ignacio I. Wistuba, Jun Wang, Dongmei Lin, Xiangyang Liu, P. Andrew Futreal, Yanning Gao
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
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Science
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Acceso en línea:https://doaj.org/article/b47899a5b32046278f07cf214de45ffc
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Sumario:Some patients present with multiple lung tumours but it is unclear whether these are metastases or individual lesions. Here, the authors use genomics techniques to demonstrate in six patients that multiple tumours have individual genetic profiles and represent separate tumours.

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