Genomic heterogeneity of multiple synchronous lung cancer

Some patients present with multiple lung tumours but it is unclear whether these are metastases or individual lesions. Here, the authors use genomics techniques to demonstrate in six patients that multiple tumours have individual genetic profiles and represent separate tumours.

Guardado en:
Detalles Bibliográficos
Autores principales: Yu Liu, Jianjun Zhang, Lin Li, Guangliang Yin, Jianhua Zhang, Shan Zheng, Hannah Cheung, Ning Wu, Ning Lu, Xizeng Mao, Longhai Yang, Jiexin Zhang, Li Zhang, Sahil Seth, Huang Chen, Xingzhi Song, Kan Liu, Yongqiang Xie, Lina Zhou, Chuanduo Zhao, Naijun Han, Wenting Chen, Susu Zhang, Longyun Chen, Wenjun Cai, Miaozhong Shen, Ningzhi Xu, Shujun Cheng, Huanming Yang, J. Jack Lee, Arlene Correa, Junya Fujimoto, Carmen Behrens, Chi-Wan Chow, William N. William, John V. Heymach, Waun Ki Hong, Stephen Swisher, Ignacio I. Wistuba, Jun Wang, Dongmei Lin, Xiangyang Liu, P. Andrew Futreal, Yanning Gao
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
Materias:
Q
Acceso en línea:https://doaj.org/article/b47899a5b32046278f07cf214de45ffc
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
id oai:doaj.org-article:b47899a5b32046278f07cf214de45ffc
record_format dspace
spelling oai:doaj.org-article:b47899a5b32046278f07cf214de45ffc2021-12-02T14:39:32ZGenomic heterogeneity of multiple synchronous lung cancer10.1038/ncomms132002041-1723https://doaj.org/article/b47899a5b32046278f07cf214de45ffc2016-10-01T00:00:00Zhttps://doi.org/10.1038/ncomms13200https://doaj.org/toc/2041-1723Some patients present with multiple lung tumours but it is unclear whether these are metastases or individual lesions. Here, the authors use genomics techniques to demonstrate in six patients that multiple tumours have individual genetic profiles and represent separate tumours.Yu LiuJianjun ZhangLin LiGuangliang YinJianhua ZhangShan ZhengHannah CheungNing WuNing LuXizeng MaoLonghai YangJiexin ZhangLi ZhangSahil SethHuang ChenXingzhi SongKan LiuYongqiang XieLina ZhouChuanduo ZhaoNaijun HanWenting ChenSusu ZhangLongyun ChenWenjun CaiLin LiMiaozhong ShenNingzhi XuShujun ChengHuanming YangJ. Jack LeeArlene CorreaJunya FujimotoCarmen BehrensChi-Wan ChowWilliam N. WilliamJohn V. HeymachWaun Ki HongStephen SwisherIgnacio I. WistubaJun WangDongmei LinXiangyang LiuP. Andrew FutrealYanning GaoNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-8 (2016)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Yu Liu
Jianjun Zhang
Lin Li
Guangliang Yin
Jianhua Zhang
Shan Zheng
Hannah Cheung
Ning Wu
Ning Lu
Xizeng Mao
Longhai Yang
Jiexin Zhang
Li Zhang
Sahil Seth
Huang Chen
Xingzhi Song
Kan Liu
Yongqiang Xie
Lina Zhou
Chuanduo Zhao
Naijun Han
Wenting Chen
Susu Zhang
Longyun Chen
Wenjun Cai
Lin Li
Miaozhong Shen
Ningzhi Xu
Shujun Cheng
Huanming Yang
J. Jack Lee
Arlene Correa
Junya Fujimoto
Carmen Behrens
Chi-Wan Chow
William N. William
John V. Heymach
Waun Ki Hong
Stephen Swisher
Ignacio I. Wistuba
Jun Wang
Dongmei Lin
Xiangyang Liu
P. Andrew Futreal
Yanning Gao
Genomic heterogeneity of multiple synchronous lung cancer
description Some patients present with multiple lung tumours but it is unclear whether these are metastases or individual lesions. Here, the authors use genomics techniques to demonstrate in six patients that multiple tumours have individual genetic profiles and represent separate tumours.
format article
author Yu Liu
Jianjun Zhang
Lin Li
Guangliang Yin
Jianhua Zhang
Shan Zheng
Hannah Cheung
Ning Wu
Ning Lu
Xizeng Mao
Longhai Yang
Jiexin Zhang
Li Zhang
Sahil Seth
Huang Chen
Xingzhi Song
Kan Liu
Yongqiang Xie
Lina Zhou
Chuanduo Zhao
Naijun Han
Wenting Chen
Susu Zhang
Longyun Chen
Wenjun Cai
Lin Li
Miaozhong Shen
Ningzhi Xu
Shujun Cheng
Huanming Yang
J. Jack Lee
Arlene Correa
Junya Fujimoto
Carmen Behrens
Chi-Wan Chow
William N. William
John V. Heymach
Waun Ki Hong
Stephen Swisher
Ignacio I. Wistuba
Jun Wang
Dongmei Lin
Xiangyang Liu
P. Andrew Futreal
Yanning Gao
author_facet Yu Liu
Jianjun Zhang
Lin Li
Guangliang Yin
Jianhua Zhang
Shan Zheng
Hannah Cheung
Ning Wu
Ning Lu
Xizeng Mao
Longhai Yang
Jiexin Zhang
Li Zhang
Sahil Seth
Huang Chen
Xingzhi Song
Kan Liu
Yongqiang Xie
Lina Zhou
Chuanduo Zhao
Naijun Han
Wenting Chen
Susu Zhang
Longyun Chen
Wenjun Cai
Lin Li
Miaozhong Shen
Ningzhi Xu
Shujun Cheng
Huanming Yang
J. Jack Lee
Arlene Correa
Junya Fujimoto
Carmen Behrens
Chi-Wan Chow
William N. William
John V. Heymach
Waun Ki Hong
Stephen Swisher
Ignacio I. Wistuba
Jun Wang
Dongmei Lin
Xiangyang Liu
P. Andrew Futreal
Yanning Gao
author_sort Yu Liu
title Genomic heterogeneity of multiple synchronous lung cancer
title_short Genomic heterogeneity of multiple synchronous lung cancer
title_full Genomic heterogeneity of multiple synchronous lung cancer
title_fullStr Genomic heterogeneity of multiple synchronous lung cancer
title_full_unstemmed Genomic heterogeneity of multiple synchronous lung cancer
title_sort genomic heterogeneity of multiple synchronous lung cancer
publisher Nature Portfolio
publishDate 2016
url https://doaj.org/article/b47899a5b32046278f07cf214de45ffc
work_keys_str_mv AT yuliu genomicheterogeneityofmultiplesynchronouslungcancer
AT jianjunzhang genomicheterogeneityofmultiplesynchronouslungcancer
AT linli genomicheterogeneityofmultiplesynchronouslungcancer
AT guangliangyin genomicheterogeneityofmultiplesynchronouslungcancer
AT jianhuazhang genomicheterogeneityofmultiplesynchronouslungcancer
AT shanzheng genomicheterogeneityofmultiplesynchronouslungcancer
AT hannahcheung genomicheterogeneityofmultiplesynchronouslungcancer
AT ningwu genomicheterogeneityofmultiplesynchronouslungcancer
AT ninglu genomicheterogeneityofmultiplesynchronouslungcancer
AT xizengmao genomicheterogeneityofmultiplesynchronouslungcancer
AT longhaiyang genomicheterogeneityofmultiplesynchronouslungcancer
AT jiexinzhang genomicheterogeneityofmultiplesynchronouslungcancer
AT lizhang genomicheterogeneityofmultiplesynchronouslungcancer
AT sahilseth genomicheterogeneityofmultiplesynchronouslungcancer
AT huangchen genomicheterogeneityofmultiplesynchronouslungcancer
AT xingzhisong genomicheterogeneityofmultiplesynchronouslungcancer
AT kanliu genomicheterogeneityofmultiplesynchronouslungcancer
AT yongqiangxie genomicheterogeneityofmultiplesynchronouslungcancer
AT linazhou genomicheterogeneityofmultiplesynchronouslungcancer
AT chuanduozhao genomicheterogeneityofmultiplesynchronouslungcancer
AT naijunhan genomicheterogeneityofmultiplesynchronouslungcancer
AT wentingchen genomicheterogeneityofmultiplesynchronouslungcancer
AT susuzhang genomicheterogeneityofmultiplesynchronouslungcancer
AT longyunchen genomicheterogeneityofmultiplesynchronouslungcancer
AT wenjuncai genomicheterogeneityofmultiplesynchronouslungcancer
AT linli genomicheterogeneityofmultiplesynchronouslungcancer
AT miaozhongshen genomicheterogeneityofmultiplesynchronouslungcancer
AT ningzhixu genomicheterogeneityofmultiplesynchronouslungcancer
AT shujuncheng genomicheterogeneityofmultiplesynchronouslungcancer
AT huanmingyang genomicheterogeneityofmultiplesynchronouslungcancer
AT jjacklee genomicheterogeneityofmultiplesynchronouslungcancer
AT arlenecorrea genomicheterogeneityofmultiplesynchronouslungcancer
AT junyafujimoto genomicheterogeneityofmultiplesynchronouslungcancer
AT carmenbehrens genomicheterogeneityofmultiplesynchronouslungcancer
AT chiwanchow genomicheterogeneityofmultiplesynchronouslungcancer
AT williamnwilliam genomicheterogeneityofmultiplesynchronouslungcancer
AT johnvheymach genomicheterogeneityofmultiplesynchronouslungcancer
AT waunkihong genomicheterogeneityofmultiplesynchronouslungcancer
AT stephenswisher genomicheterogeneityofmultiplesynchronouslungcancer
AT ignacioiwistuba genomicheterogeneityofmultiplesynchronouslungcancer
AT junwang genomicheterogeneityofmultiplesynchronouslungcancer
AT dongmeilin genomicheterogeneityofmultiplesynchronouslungcancer
AT xiangyangliu genomicheterogeneityofmultiplesynchronouslungcancer
AT pandrewfutreal genomicheterogeneityofmultiplesynchronouslungcancer
AT yanninggao genomicheterogeneityofmultiplesynchronouslungcancer
_version_ 1718390612637515776