Genomic heterogeneity of multiple synchronous lung cancer
Some patients present with multiple lung tumours but it is unclear whether these are metastases or individual lesions. Here, the authors use genomics techniques to demonstrate in six patients that multiple tumours have individual genetic profiles and represent separate tumours.
Guardado en:
Autores principales: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2016
|
Materias: | |
Acceso en línea: | https://doaj.org/article/b47899a5b32046278f07cf214de45ffc |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
id |
oai:doaj.org-article:b47899a5b32046278f07cf214de45ffc |
---|---|
record_format |
dspace |
spelling |
oai:doaj.org-article:b47899a5b32046278f07cf214de45ffc2021-12-02T14:39:32ZGenomic heterogeneity of multiple synchronous lung cancer10.1038/ncomms132002041-1723https://doaj.org/article/b47899a5b32046278f07cf214de45ffc2016-10-01T00:00:00Zhttps://doi.org/10.1038/ncomms13200https://doaj.org/toc/2041-1723Some patients present with multiple lung tumours but it is unclear whether these are metastases or individual lesions. Here, the authors use genomics techniques to demonstrate in six patients that multiple tumours have individual genetic profiles and represent separate tumours.Yu LiuJianjun ZhangLin LiGuangliang YinJianhua ZhangShan ZhengHannah CheungNing WuNing LuXizeng MaoLonghai YangJiexin ZhangLi ZhangSahil SethHuang ChenXingzhi SongKan LiuYongqiang XieLina ZhouChuanduo ZhaoNaijun HanWenting ChenSusu ZhangLongyun ChenWenjun CaiLin LiMiaozhong ShenNingzhi XuShujun ChengHuanming YangJ. Jack LeeArlene CorreaJunya FujimotoCarmen BehrensChi-Wan ChowWilliam N. WilliamJohn V. HeymachWaun Ki HongStephen SwisherIgnacio I. WistubaJun WangDongmei LinXiangyang LiuP. Andrew FutrealYanning GaoNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-8 (2016) |
institution |
DOAJ |
collection |
DOAJ |
language |
EN |
topic |
Science Q |
spellingShingle |
Science Q Yu Liu Jianjun Zhang Lin Li Guangliang Yin Jianhua Zhang Shan Zheng Hannah Cheung Ning Wu Ning Lu Xizeng Mao Longhai Yang Jiexin Zhang Li Zhang Sahil Seth Huang Chen Xingzhi Song Kan Liu Yongqiang Xie Lina Zhou Chuanduo Zhao Naijun Han Wenting Chen Susu Zhang Longyun Chen Wenjun Cai Lin Li Miaozhong Shen Ningzhi Xu Shujun Cheng Huanming Yang J. Jack Lee Arlene Correa Junya Fujimoto Carmen Behrens Chi-Wan Chow William N. William John V. Heymach Waun Ki Hong Stephen Swisher Ignacio I. Wistuba Jun Wang Dongmei Lin Xiangyang Liu P. Andrew Futreal Yanning Gao Genomic heterogeneity of multiple synchronous lung cancer |
description |
Some patients present with multiple lung tumours but it is unclear whether these are metastases or individual lesions. Here, the authors use genomics techniques to demonstrate in six patients that multiple tumours have individual genetic profiles and represent separate tumours. |
format |
article |
author |
Yu Liu Jianjun Zhang Lin Li Guangliang Yin Jianhua Zhang Shan Zheng Hannah Cheung Ning Wu Ning Lu Xizeng Mao Longhai Yang Jiexin Zhang Li Zhang Sahil Seth Huang Chen Xingzhi Song Kan Liu Yongqiang Xie Lina Zhou Chuanduo Zhao Naijun Han Wenting Chen Susu Zhang Longyun Chen Wenjun Cai Lin Li Miaozhong Shen Ningzhi Xu Shujun Cheng Huanming Yang J. Jack Lee Arlene Correa Junya Fujimoto Carmen Behrens Chi-Wan Chow William N. William John V. Heymach Waun Ki Hong Stephen Swisher Ignacio I. Wistuba Jun Wang Dongmei Lin Xiangyang Liu P. Andrew Futreal Yanning Gao |
author_facet |
Yu Liu Jianjun Zhang Lin Li Guangliang Yin Jianhua Zhang Shan Zheng Hannah Cheung Ning Wu Ning Lu Xizeng Mao Longhai Yang Jiexin Zhang Li Zhang Sahil Seth Huang Chen Xingzhi Song Kan Liu Yongqiang Xie Lina Zhou Chuanduo Zhao Naijun Han Wenting Chen Susu Zhang Longyun Chen Wenjun Cai Lin Li Miaozhong Shen Ningzhi Xu Shujun Cheng Huanming Yang J. Jack Lee Arlene Correa Junya Fujimoto Carmen Behrens Chi-Wan Chow William N. William John V. Heymach Waun Ki Hong Stephen Swisher Ignacio I. Wistuba Jun Wang Dongmei Lin Xiangyang Liu P. Andrew Futreal Yanning Gao |
author_sort |
Yu Liu |
title |
Genomic heterogeneity of multiple synchronous lung cancer |
title_short |
Genomic heterogeneity of multiple synchronous lung cancer |
title_full |
Genomic heterogeneity of multiple synchronous lung cancer |
title_fullStr |
Genomic heterogeneity of multiple synchronous lung cancer |
title_full_unstemmed |
Genomic heterogeneity of multiple synchronous lung cancer |
title_sort |
genomic heterogeneity of multiple synchronous lung cancer |
publisher |
Nature Portfolio |
publishDate |
2016 |
url |
https://doaj.org/article/b47899a5b32046278f07cf214de45ffc |
work_keys_str_mv |
AT yuliu genomicheterogeneityofmultiplesynchronouslungcancer AT jianjunzhang genomicheterogeneityofmultiplesynchronouslungcancer AT linli genomicheterogeneityofmultiplesynchronouslungcancer AT guangliangyin genomicheterogeneityofmultiplesynchronouslungcancer AT jianhuazhang genomicheterogeneityofmultiplesynchronouslungcancer AT shanzheng genomicheterogeneityofmultiplesynchronouslungcancer AT hannahcheung genomicheterogeneityofmultiplesynchronouslungcancer AT ningwu genomicheterogeneityofmultiplesynchronouslungcancer AT ninglu genomicheterogeneityofmultiplesynchronouslungcancer AT xizengmao genomicheterogeneityofmultiplesynchronouslungcancer AT longhaiyang genomicheterogeneityofmultiplesynchronouslungcancer AT jiexinzhang genomicheterogeneityofmultiplesynchronouslungcancer AT lizhang genomicheterogeneityofmultiplesynchronouslungcancer AT sahilseth genomicheterogeneityofmultiplesynchronouslungcancer AT huangchen genomicheterogeneityofmultiplesynchronouslungcancer AT xingzhisong genomicheterogeneityofmultiplesynchronouslungcancer AT kanliu genomicheterogeneityofmultiplesynchronouslungcancer AT yongqiangxie genomicheterogeneityofmultiplesynchronouslungcancer AT linazhou genomicheterogeneityofmultiplesynchronouslungcancer AT chuanduozhao genomicheterogeneityofmultiplesynchronouslungcancer AT naijunhan genomicheterogeneityofmultiplesynchronouslungcancer AT wentingchen genomicheterogeneityofmultiplesynchronouslungcancer AT susuzhang genomicheterogeneityofmultiplesynchronouslungcancer AT longyunchen genomicheterogeneityofmultiplesynchronouslungcancer AT wenjuncai genomicheterogeneityofmultiplesynchronouslungcancer AT linli genomicheterogeneityofmultiplesynchronouslungcancer AT miaozhongshen genomicheterogeneityofmultiplesynchronouslungcancer AT ningzhixu genomicheterogeneityofmultiplesynchronouslungcancer AT shujuncheng genomicheterogeneityofmultiplesynchronouslungcancer AT huanmingyang genomicheterogeneityofmultiplesynchronouslungcancer AT jjacklee genomicheterogeneityofmultiplesynchronouslungcancer AT arlenecorrea genomicheterogeneityofmultiplesynchronouslungcancer AT junyafujimoto genomicheterogeneityofmultiplesynchronouslungcancer AT carmenbehrens genomicheterogeneityofmultiplesynchronouslungcancer AT chiwanchow genomicheterogeneityofmultiplesynchronouslungcancer AT williamnwilliam genomicheterogeneityofmultiplesynchronouslungcancer AT johnvheymach genomicheterogeneityofmultiplesynchronouslungcancer AT waunkihong genomicheterogeneityofmultiplesynchronouslungcancer AT stephenswisher genomicheterogeneityofmultiplesynchronouslungcancer AT ignacioiwistuba genomicheterogeneityofmultiplesynchronouslungcancer AT junwang genomicheterogeneityofmultiplesynchronouslungcancer AT dongmeilin genomicheterogeneityofmultiplesynchronouslungcancer AT xiangyangliu genomicheterogeneityofmultiplesynchronouslungcancer AT pandrewfutreal genomicheterogeneityofmultiplesynchronouslungcancer AT yanninggao genomicheterogeneityofmultiplesynchronouslungcancer |
_version_ |
1718390612637515776 |