Tryptophan Metabolism in Bipolar Disorder in a Longitudinal Setting

Tryptophan Metabolism in Bipolar Disorder in a Longitudinal Setting

Immune-mediated inflammatory processes and oxidative stress are involved in the aetiopathogenesis of bipolar disorder (BD) and weight-associated comorbidities. Tryptophan breakdown via indoleamine 2,3-dioxygenase-1 (IDO-1) along the kynurenine axis concomitant with a pro-inflammatory state was found...

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Main Authors: Frederike T. Fellendorf, Johanna M. Gostner, Melanie Lenger, Martina Platzer, Armin Birner, Alexander Maget, Robert Queissner, Adelina Tmava-Berisha, Cornelia A. Pater, Michaela Ratzenhofer, Jolana Wagner-Skacel, Susanne A. Bengesser, Nina Dalkner, Dietmar Fuchs, Eva Z. Reininghaus
Format: article
Language:EN
Published: MDPI AG 2021
Subjects:
bipolar disorder
psychoneuroimmunology
kynurenine to tryptophan ratio
tryptophan metabolism
IDO-1
Therapeutics. Pharmacology
RM1-950
Online Access:https://doaj.org/article/b47b6454846a4d7cae08521cf3d751be
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https://doaj.org/article/b47b6454846a4d7cae08521cf3d751be

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