Nanoscale metal-organic frameworks for mitochondria-targeted radiotherapy-radiodynamic therapy

Photosensitizers delivered to mitochondria of cancer cells can enhance photodynamic therapy. Here, the authors report mitochondria-targeted radiation therapy and radiodynamic therapy of colorectal cancer models with a cationic nanoscale metal-organic framework to overcome shallow light penetration o...

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Autores principales:	Kaiyuan Ni, Guangxu Lan, Samuel S. Veroneau, Xiaopin Duan, Yang Song, Wenbin Lin
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/b48e9debae774852a0d394aca2141437
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spelling	oai:doaj.org-article:b48e9debae774852a0d394aca21414372021-12-02T15:34:07ZNanoscale metal-organic frameworks for mitochondria-targeted radiotherapy-radiodynamic therapy10.1038/s41467-018-06655-72041-1723https://doaj.org/article/b48e9debae774852a0d394aca21414372018-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-06655-7https://doaj.org/toc/2041-1723Photosensitizers delivered to mitochondria of cancer cells can enhance photodynamic therapy. Here, the authors report mitochondria-targeted radiation therapy and radiodynamic therapy of colorectal cancer models with a cationic nanoscale metal-organic framework to overcome shallow light penetration of Ru-based photosensitizers.Kaiyuan NiGuangxu LanSamuel S. VeroneauXiaopin DuanYang SongWenbin LinNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Kaiyuan Ni Guangxu Lan Samuel S. Veroneau Xiaopin Duan Yang Song Wenbin Lin Nanoscale metal-organic frameworks for mitochondria-targeted radiotherapy-radiodynamic therapy
description	Photosensitizers delivered to mitochondria of cancer cells can enhance photodynamic therapy. Here, the authors report mitochondria-targeted radiation therapy and radiodynamic therapy of colorectal cancer models with a cationic nanoscale metal-organic framework to overcome shallow light penetration of Ru-based photosensitizers.
format	article
author	Kaiyuan Ni Guangxu Lan Samuel S. Veroneau Xiaopin Duan Yang Song Wenbin Lin
author_facet	Kaiyuan Ni Guangxu Lan Samuel S. Veroneau Xiaopin Duan Yang Song Wenbin Lin
author_sort	Kaiyuan Ni
title	Nanoscale metal-organic frameworks for mitochondria-targeted radiotherapy-radiodynamic therapy
title_short	Nanoscale metal-organic frameworks for mitochondria-targeted radiotherapy-radiodynamic therapy
title_full	Nanoscale metal-organic frameworks for mitochondria-targeted radiotherapy-radiodynamic therapy
title_fullStr	Nanoscale metal-organic frameworks for mitochondria-targeted radiotherapy-radiodynamic therapy
title_full_unstemmed	Nanoscale metal-organic frameworks for mitochondria-targeted radiotherapy-radiodynamic therapy
title_sort	nanoscale metal-organic frameworks for mitochondria-targeted radiotherapy-radiodynamic therapy
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/b48e9debae774852a0d394aca2141437
work_keys_str_mv	AT kaiyuanni nanoscalemetalorganicframeworksformitochondriatargetedradiotherapyradiodynamictherapy AT guangxulan nanoscalemetalorganicframeworksformitochondriatargetedradiotherapyradiodynamictherapy AT samuelsveroneau nanoscalemetalorganicframeworksformitochondriatargetedradiotherapyradiodynamictherapy AT xiaopinduan nanoscalemetalorganicframeworksformitochondriatargetedradiotherapyradiodynamictherapy AT yangsong nanoscalemetalorganicframeworksformitochondriatargetedradiotherapyradiodynamictherapy AT wenbinlin nanoscalemetalorganicframeworksformitochondriatargetedradiotherapyradiodynamictherapy
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Nanoscale metal-organic frameworks for mitochondria-targeted radiotherapy-radiodynamic therapy

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