Complementary mesoscale dynamics of spectrin and acto-myosin shape membrane territories during mechanoresponse

The cell cortex that supports the plasma membrane contains spectrin, a protein that interacts with the acto-myosin cytoskeleton. Here, the authors analyze spectrin behavior during cellular mechanoresponse and membrane trafficking, and observe spectrin regulation by myosin-driven contractility.

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Detalles Bibliográficos
Autores principales: Andrea Ghisleni, Camilla Galli, Pascale Monzo, Flora Ascione, Marc-Antoine Fardin, Giorgio Scita, Qingsen Li, Paolo Maiuri, Nils C. Gauthier
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/b49028cf2ff84964a7c443b6f61b4c67
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Sumario:The cell cortex that supports the plasma membrane contains spectrin, a protein that interacts with the acto-myosin cytoskeleton. Here, the authors analyze spectrin behavior during cellular mechanoresponse and membrane trafficking, and observe spectrin regulation by myosin-driven contractility.