Translational Control of the SigR-Directed Oxidative Stress Response in <italic toggle="yes">Streptomyces</italic> via IF3-Mediated Repression of a Noncanonical GTC Start Codon

Translational Control of the SigR-Directed Oxidative Stress Response in <italic toggle="yes">Streptomyces</italic> via IF3-Mediated Repression of a Noncanonical GTC Start Codon

ABSTRACT The major oxidative stress response in Streptomyces is controlled by the sigma factor SigR and its cognate antisigma factor RsrA, and SigR activity is tightly controlled through multiple mechanisms at both the transcriptional and posttranslational levels. Here we show that sigR has a highly...

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Autores principales: Morgan A. Feeney, Govind Chandra, Kim C. Findlay, Mark S. B. Paget, Mark J. Buttner
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2017
Materias:
IF3
noncanonical start codon
oxidative stress
sigma factors
translation initiation
Microbiology
QR1-502
Acceso en línea:https://doaj.org/article/b498b2ea2384475489dd613133b4c885
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