Proline codon pair selection determines ribosome pausing strength and translation efficiency in bacteria
Ralph Krafczyk et al. demonstrate that both proline codon usage and prolyl-tRNA abundance affect mRNA translation rates of polyproline-motifs in bacteria. These results provide additional insight into sequence-specific translation regulation.
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Main Authors: | Ralph Krafczyk, Fei Qi, Alina Sieber, Judith Mehler, Kirsten Jung, Dmitrij Frishman, Jürgen Lassak |
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Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2021
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Online Access: | https://doaj.org/article/b4af811cdec04b86b9f2d2ab3de7d104 |
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