SARS-CoV-2 seroprevalence and neutralizing activity in donor and patient blood

Highly accurate antibody tests for SARS-CoV-2 are needed for surveillance in low-prevalence populations. Here, the authors find seroprevalence of less than 1% in two San Francisco Bay Area populations at the beginning of April, and that seroreactivity is generally predictive of in vitro neutralising...

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Autores principales: Dianna L. Ng, Gregory M. Goldgof, Brian R. Shy, Andrew G. Levine, Joanna Balcerek, Sagar P. Bapat, John Prostko, Mary Rodgers, Kelly Coller, Sandra Pearce, Sergej Franz, Li Du, Mars Stone, Satish K. Pillai, Alicia Sotomayor-Gonzalez, Venice Servellita, Claudia Sanchez San Martin, Andrea Granados, Dustin R. Glasner, Lucy M. Han, Kent Truong, Naomi Akagi, David N. Nguyen, Neil M. Neumann, Daniel Qazi, Elaine Hsu, Wei Gu, Yale A. Santos, Brian Custer, Valerie Green, Phillip Williamson, Nancy K. Hills, Chuanyi M. Lu, Jeffrey D. Whitman, Susan L. Stramer, Candace Wang, Kevin Reyes, Jill M. C. Hakim, Kirk Sujishi, Fariba Alazzeh, Lori Pham, Edward Thornborrow, Ching-Ying Oon, Steve Miller, Theodore Kurtz, Graham Simmons, John Hackett, Michael P. Busch, Charles Y. Chiu
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Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/b4b0b2c17edb43c98ec84b755fb3600a
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spelling oai:doaj.org-article:b4b0b2c17edb43c98ec84b755fb3600a2021-12-02T17:23:48ZSARS-CoV-2 seroprevalence and neutralizing activity in donor and patient blood10.1038/s41467-020-18468-82041-1723https://doaj.org/article/b4b0b2c17edb43c98ec84b755fb3600a2020-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-18468-8https://doaj.org/toc/2041-1723Highly accurate antibody tests for SARS-CoV-2 are needed for surveillance in low-prevalence populations. Here, the authors find seroprevalence of less than 1% in two San Francisco Bay Area populations at the beginning of April, and that seroreactivity is generally predictive of in vitro neutralising activity.Dianna L. NgGregory M. GoldgofBrian R. ShyAndrew G. LevineJoanna BalcerekSagar P. BapatJohn ProstkoMary RodgersKelly CollerSandra PearceSergej FranzLi DuMars StoneSatish K. PillaiAlicia Sotomayor-GonzalezVenice ServellitaClaudia Sanchez San MartinAndrea GranadosDustin R. GlasnerLucy M. HanKent TruongNaomi AkagiDavid N. NguyenNeil M. NeumannDaniel QaziElaine HsuWei GuYale A. SantosBrian CusterValerie GreenPhillip WilliamsonNancy K. HillsChuanyi M. LuJeffrey D. WhitmanSusan L. StramerCandace WangKevin ReyesJill M. C. HakimKirk SujishiFariba AlazzehLori PhamEdward ThornborrowChing-Ying OonSteve MillerTheodore KurtzGraham SimmonsJohn HackettMichael P. BuschCharles Y. ChiuNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-7 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Dianna L. Ng
Gregory M. Goldgof
Brian R. Shy
Andrew G. Levine
Joanna Balcerek
Sagar P. Bapat
John Prostko
Mary Rodgers
Kelly Coller
Sandra Pearce
Sergej Franz
Li Du
Mars Stone
Satish K. Pillai
Alicia Sotomayor-Gonzalez
Venice Servellita
Claudia Sanchez San Martin
Andrea Granados
Dustin R. Glasner
Lucy M. Han
Kent Truong
Naomi Akagi
David N. Nguyen
Neil M. Neumann
Daniel Qazi
Elaine Hsu
Wei Gu
Yale A. Santos
Brian Custer
Valerie Green
Phillip Williamson
Nancy K. Hills
Chuanyi M. Lu
Jeffrey D. Whitman
Susan L. Stramer
Candace Wang
Kevin Reyes
Jill M. C. Hakim
Kirk Sujishi
Fariba Alazzeh
Lori Pham
Edward Thornborrow
Ching-Ying Oon
Steve Miller
Theodore Kurtz
Graham Simmons
John Hackett
Michael P. Busch
Charles Y. Chiu
SARS-CoV-2 seroprevalence and neutralizing activity in donor and patient blood
description Highly accurate antibody tests for SARS-CoV-2 are needed for surveillance in low-prevalence populations. Here, the authors find seroprevalence of less than 1% in two San Francisco Bay Area populations at the beginning of April, and that seroreactivity is generally predictive of in vitro neutralising activity.
format article
author Dianna L. Ng
Gregory M. Goldgof
Brian R. Shy
Andrew G. Levine
Joanna Balcerek
Sagar P. Bapat
John Prostko
Mary Rodgers
Kelly Coller
Sandra Pearce
Sergej Franz
Li Du
Mars Stone
Satish K. Pillai
Alicia Sotomayor-Gonzalez
Venice Servellita
Claudia Sanchez San Martin
Andrea Granados
Dustin R. Glasner
Lucy M. Han
Kent Truong
Naomi Akagi
David N. Nguyen
Neil M. Neumann
Daniel Qazi
Elaine Hsu
Wei Gu
Yale A. Santos
Brian Custer
Valerie Green
Phillip Williamson
Nancy K. Hills
Chuanyi M. Lu
Jeffrey D. Whitman
Susan L. Stramer
Candace Wang
Kevin Reyes
Jill M. C. Hakim
Kirk Sujishi
Fariba Alazzeh
Lori Pham
Edward Thornborrow
Ching-Ying Oon
Steve Miller
Theodore Kurtz
Graham Simmons
John Hackett
Michael P. Busch
Charles Y. Chiu
author_facet Dianna L. Ng
Gregory M. Goldgof
Brian R. Shy
Andrew G. Levine
Joanna Balcerek
Sagar P. Bapat
John Prostko
Mary Rodgers
Kelly Coller
Sandra Pearce
Sergej Franz
Li Du
Mars Stone
Satish K. Pillai
Alicia Sotomayor-Gonzalez
Venice Servellita
Claudia Sanchez San Martin
Andrea Granados
Dustin R. Glasner
Lucy M. Han
Kent Truong
Naomi Akagi
David N. Nguyen
Neil M. Neumann
Daniel Qazi
Elaine Hsu
Wei Gu
Yale A. Santos
Brian Custer
Valerie Green
Phillip Williamson
Nancy K. Hills
Chuanyi M. Lu
Jeffrey D. Whitman
Susan L. Stramer
Candace Wang
Kevin Reyes
Jill M. C. Hakim
Kirk Sujishi
Fariba Alazzeh
Lori Pham
Edward Thornborrow
Ching-Ying Oon
Steve Miller
Theodore Kurtz
Graham Simmons
John Hackett
Michael P. Busch
Charles Y. Chiu
author_sort Dianna L. Ng
title SARS-CoV-2 seroprevalence and neutralizing activity in donor and patient blood
title_short SARS-CoV-2 seroprevalence and neutralizing activity in donor and patient blood
title_full SARS-CoV-2 seroprevalence and neutralizing activity in donor and patient blood
title_fullStr SARS-CoV-2 seroprevalence and neutralizing activity in donor and patient blood
title_full_unstemmed SARS-CoV-2 seroprevalence and neutralizing activity in donor and patient blood
title_sort sars-cov-2 seroprevalence and neutralizing activity in donor and patient blood
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/b4b0b2c17edb43c98ec84b755fb3600a
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