A double-hit of stress and low-grade inflammation on functional brain network mediates posttraumatic stress symptoms

Low-grade systemic inflammation and stress increase vulnerability to neuropsychiatric disorders. Here, the authors show that inflammation and stress-induced changes in higher order cognitive networks increase vulnerability to posttraumatic stress disorder.

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Detalles Bibliográficos
Autores principales: Jungyoon Kim, Sujung Yoon, Suji Lee, Haejin Hong, Eunji Ha, Yoonji Joo, Eun Hee Lee, In Kyoon Lyoo
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/b4b1ce9d68d349c6aadca6037f97ab64
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Descripción
Sumario:Low-grade systemic inflammation and stress increase vulnerability to neuropsychiatric disorders. Here, the authors show that inflammation and stress-induced changes in higher order cognitive networks increase vulnerability to posttraumatic stress disorder.