LISTERIA MONOCYTOGENES: SPREADING AND MECHANISMS OF IMMUNE RESPONSE

Abstract. Gram-positive bacteria Listeria monocytogenes (LM) the causative agent of listeriosis is one of the pathogens entering to the human organism by food products. The listeriosis is one of the oldest experimental infection and LM is the classic object for study of cell immunity mechanisms. It...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	I. F. Antoshina, M. V. Mezentseva
Formato:	article
Lenguaje:	RU
Publicado:	Sankt-Peterburg : NIIÈM imeni Pastera 2014
Materias:	listeria monocytogenes listeriosis immunity cytokines interleukins interferon Infectious and parasitic diseases RC109-216
Acceso en línea:	https://doaj.org/article/b4b809b3a2c3436f9b872d6051f441c5
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:b4b809b3a2c3436f9b872d6051f441c5
record_format	dspace
spelling	oai:doaj.org-article:b4b809b3a2c3436f9b872d6051f441c52021-11-22T07:09:45ZLISTERIA MONOCYTOGENES: SPREADING AND MECHANISMS OF IMMUNE RESPONSE2220-76192313-739810.15789/2220-7619-2012-3-627-634https://doaj.org/article/b4b809b3a2c3436f9b872d6051f441c52014-07-01T00:00:00Zhttps://www.iimmun.ru/iimm/article/view/78https://doaj.org/toc/2220-7619https://doaj.org/toc/2313-7398Abstract. Gram-positive bacteria Listeria monocytogenes (LM) the causative agent of listeriosis is one of the pathogens entering to the human organism by food products. The listeriosis is one of the oldest experimental infection and LM is the classic object for study of cell immunity mechanisms. It was established that virulent bacteria L. monocytogenes induce infected immune cells to avoid own protective response. The authors conducted experiments to study changes in immune response indicators in mice in the different stages of infection (during 3–5 days) caused by L. monocytogenes EGDe (wt) strain and bacteria of isogeneic strains with mutations in genes controlled production of PAMPs (d28, i28). Analysis of published data and obtained results of this study allows to make a conclusion that immune response in listeriosis plays an important role and it depends on pathogen strain, bacteria doses and another condition of infection. Conducted study can be useful in case of choosing of treatment tactic of disease caused by Listeria monocytogenes, and, probable another diseases, caused by intracellular bacteria.I. F. AntoshinaM. V. MezentsevaSankt-Peterburg : NIIÈM imeni Pasteraarticlelisteria monocytogeneslisteriosisimmunitycytokinesinterleukinsinterferonInfectious and parasitic diseasesRC109-216RUInfekciâ i Immunitet, Vol 2, Iss 3, Pp 627-634 (2014)
institution	DOAJ
collection	DOAJ
language	RU
topic	listeria monocytogenes listeriosis immunity cytokines interleukins interferon Infectious and parasitic diseases RC109-216
spellingShingle	listeria monocytogenes listeriosis immunity cytokines interleukins interferon Infectious and parasitic diseases RC109-216 I. F. Antoshina M. V. Mezentseva LISTERIA MONOCYTOGENES: SPREADING AND MECHANISMS OF IMMUNE RESPONSE
description	Abstract. Gram-positive bacteria Listeria monocytogenes (LM) the causative agent of listeriosis is one of the pathogens entering to the human organism by food products. The listeriosis is one of the oldest experimental infection and LM is the classic object for study of cell immunity mechanisms. It was established that virulent bacteria L. monocytogenes induce infected immune cells to avoid own protective response. The authors conducted experiments to study changes in immune response indicators in mice in the different stages of infection (during 3–5 days) caused by L. monocytogenes EGDe (wt) strain and bacteria of isogeneic strains with mutations in genes controlled production of PAMPs (d28, i28). Analysis of published data and obtained results of this study allows to make a conclusion that immune response in listeriosis plays an important role and it depends on pathogen strain, bacteria doses and another condition of infection. Conducted study can be useful in case of choosing of treatment tactic of disease caused by Listeria monocytogenes, and, probable another diseases, caused by intracellular bacteria.
format	article
author	I. F. Antoshina M. V. Mezentseva
author_facet	I. F. Antoshina M. V. Mezentseva
author_sort	I. F. Antoshina
title	LISTERIA MONOCYTOGENES: SPREADING AND MECHANISMS OF IMMUNE RESPONSE
title_short	LISTERIA MONOCYTOGENES: SPREADING AND MECHANISMS OF IMMUNE RESPONSE
title_full	LISTERIA MONOCYTOGENES: SPREADING AND MECHANISMS OF IMMUNE RESPONSE
title_fullStr	LISTERIA MONOCYTOGENES: SPREADING AND MECHANISMS OF IMMUNE RESPONSE
title_full_unstemmed	LISTERIA MONOCYTOGENES: SPREADING AND MECHANISMS OF IMMUNE RESPONSE
title_sort	listeria monocytogenes: spreading and mechanisms of immune response
publisher	Sankt-Peterburg : NIIÈM imeni Pastera
publishDate	2014
url	https://doaj.org/article/b4b809b3a2c3436f9b872d6051f441c5
work_keys_str_mv	AT ifantoshina listeriamonocytogenesspreadingandmechanismsofimmuneresponse AT mvmezentseva listeriamonocytogenesspreadingandmechanismsofimmuneresponse
_version_	1718418062867169280

LISTERIA MONOCYTOGENES: SPREADING AND MECHANISMS OF IMMUNE RESPONSE

Ejemplares similares