Dynamin-related protein 1 deficiency accelerates lipopolysaccharide-induced acute liver injury and inflammation in mice

Wang et al. report that deficiency of dynamin-related protein 1, which controls mitochondrial fission, accelerates lipopolysaccharide-induced acute liver injury and inflammation in mice. Thus, they highlight mitochondria dynamics dysfunction as a new mechanism of liver disease development.

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Autores principales:	Lixiang Wang, Xin Li, Yuki Hanada, Nao Hasuzawa, Yoshinori Moriyama, Masatoshi Nomura, Ken Yamamoto
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Biology (General) QH301-705.5
Acceso en línea:	https://doaj.org/article/b4b859d6ece348c3a063d390f5e00ce9
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spelling	oai:doaj.org-article:b4b859d6ece348c3a063d390f5e00ce92021-12-02T16:17:27ZDynamin-related protein 1 deficiency accelerates lipopolysaccharide-induced acute liver injury and inflammation in mice10.1038/s42003-021-02413-62399-3642https://doaj.org/article/b4b859d6ece348c3a063d390f5e00ce92021-07-01T00:00:00Zhttps://doi.org/10.1038/s42003-021-02413-6https://doaj.org/toc/2399-3642Wang et al. report that deficiency of dynamin-related protein 1, which controls mitochondrial fission, accelerates lipopolysaccharide-induced acute liver injury and inflammation in mice. Thus, they highlight mitochondria dynamics dysfunction as a new mechanism of liver disease development.Lixiang WangXin LiYuki HanadaNao HasuzawaYoshinori MoriyamaMasatoshi NomuraKen YamamotoNature PortfolioarticleBiology (General)QH301-705.5ENCommunications Biology, Vol 4, Iss 1, Pp 1-14 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Biology (General) QH301-705.5
spellingShingle	Biology (General) QH301-705.5 Lixiang Wang Xin Li Yuki Hanada Nao Hasuzawa Yoshinori Moriyama Masatoshi Nomura Ken Yamamoto Dynamin-related protein 1 deficiency accelerates lipopolysaccharide-induced acute liver injury and inflammation in mice
description	Wang et al. report that deficiency of dynamin-related protein 1, which controls mitochondrial fission, accelerates lipopolysaccharide-induced acute liver injury and inflammation in mice. Thus, they highlight mitochondria dynamics dysfunction as a new mechanism of liver disease development.
format	article
author	Lixiang Wang Xin Li Yuki Hanada Nao Hasuzawa Yoshinori Moriyama Masatoshi Nomura Ken Yamamoto
author_facet	Lixiang Wang Xin Li Yuki Hanada Nao Hasuzawa Yoshinori Moriyama Masatoshi Nomura Ken Yamamoto
author_sort	Lixiang Wang
title	Dynamin-related protein 1 deficiency accelerates lipopolysaccharide-induced acute liver injury and inflammation in mice
title_short	Dynamin-related protein 1 deficiency accelerates lipopolysaccharide-induced acute liver injury and inflammation in mice
title_full	Dynamin-related protein 1 deficiency accelerates lipopolysaccharide-induced acute liver injury and inflammation in mice
title_fullStr	Dynamin-related protein 1 deficiency accelerates lipopolysaccharide-induced acute liver injury and inflammation in mice
title_full_unstemmed	Dynamin-related protein 1 deficiency accelerates lipopolysaccharide-induced acute liver injury and inflammation in mice
title_sort	dynamin-related protein 1 deficiency accelerates lipopolysaccharide-induced acute liver injury and inflammation in mice
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/b4b859d6ece348c3a063d390f5e00ce9
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Dynamin-related protein 1 deficiency accelerates lipopolysaccharide-induced acute liver injury and inflammation in mice

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