Mortality in individuals treated with COVID-19 convalescent plasma varies with the geographic provenance of donors

Regional differences in SARS-CoV-2 variants may affect treatment outcome. Here, the authors show that near-sourced convalescent plasma has higher efficacy, as defined by death within 30 days of transfusion, than plasma sourced more than 150 miles away.

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Autores principales: Katie L. Kunze, Patrick W. Johnson, Noud van Helmond, Jonathon W. Senefeld, Molly M. Petersen, Stephen A. Klassen, Chad C. Wiggins, Allan M. Klompas, Katelyn A. Bruno, John R. Mills, Elitza S. Theel, Matthew R. Buras, Michael A. Golafshar, Matthew A. Sexton, Juan C. Diaz Soto, Sarah E. Baker, John R. A. Shepherd, Nicole C. Verdun, Peter Marks, Nigel S. Paneth, DeLisa Fairweather, R. Scott Wright, Camille M. van Buskirk, Jeffrey L. Winters, James R. Stubbs, Katherine A. Senese, Michaela C. Pletsch, Zachary A. Buchholtz, Robert F. Rea, Vitaly Herasevich, Emily R. Whelan, Andrew J. Clayburn, Kathryn F. Larson, Juan G. Ripoll, Kylie J. Andersen, Elizabeth R. Lesser, Matthew N. P. Vogt, Joshua J. Dennis, Riley J. Regimbal, Philippe R. Bauer, Janis E. Blair, Arturo Casadevall, Rickey E. Carter, Michael J. Joyner
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Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/b4c2e18825314c909846a2c6aed3901d
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spelling oai:doaj.org-article:b4c2e18825314c909846a2c6aed3901d2021-12-02T18:50:57ZMortality in individuals treated with COVID-19 convalescent plasma varies with the geographic provenance of donors10.1038/s41467-021-25113-52041-1723https://doaj.org/article/b4c2e18825314c909846a2c6aed3901d2021-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-25113-5https://doaj.org/toc/2041-1723Regional differences in SARS-CoV-2 variants may affect treatment outcome. Here, the authors show that near-sourced convalescent plasma has higher efficacy, as defined by death within 30 days of transfusion, than plasma sourced more than 150 miles away.Katie L. KunzePatrick W. JohnsonNoud van HelmondJonathon W. SenefeldMolly M. PetersenStephen A. KlassenChad C. WigginsAllan M. KlompasKatelyn A. BrunoJohn R. MillsElitza S. TheelMatthew R. BurasMichael A. GolafsharMatthew A. SextonJuan C. Diaz SotoSarah E. BakerJohn R. A. ShepherdNicole C. VerdunPeter MarksNigel S. PanethDeLisa FairweatherR. Scott WrightCamille M. van BuskirkJeffrey L. WintersJames R. StubbsKatherine A. SeneseMichaela C. PletschZachary A. BuchholtzRobert F. ReaVitaly HerasevichEmily R. WhelanAndrew J. ClayburnKathryn F. LarsonJuan G. RipollKylie J. AndersenElizabeth R. LesserMatthew N. P. VogtJoshua J. DennisRiley J. RegimbalPhilippe R. BauerJanis E. BlairArturo CasadevallRickey E. CarterMichael J. JoynerNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-6 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Katie L. Kunze
Patrick W. Johnson
Noud van Helmond
Jonathon W. Senefeld
Molly M. Petersen
Stephen A. Klassen
Chad C. Wiggins
Allan M. Klompas
Katelyn A. Bruno
John R. Mills
Elitza S. Theel
Matthew R. Buras
Michael A. Golafshar
Matthew A. Sexton
Juan C. Diaz Soto
Sarah E. Baker
John R. A. Shepherd
Nicole C. Verdun
Peter Marks
Nigel S. Paneth
DeLisa Fairweather
R. Scott Wright
Camille M. van Buskirk
Jeffrey L. Winters
James R. Stubbs
Katherine A. Senese
Michaela C. Pletsch
Zachary A. Buchholtz
Robert F. Rea
Vitaly Herasevich
Emily R. Whelan
Andrew J. Clayburn
Kathryn F. Larson
Juan G. Ripoll
Kylie J. Andersen
Elizabeth R. Lesser
Matthew N. P. Vogt
Joshua J. Dennis
Riley J. Regimbal
Philippe R. Bauer
Janis E. Blair
Arturo Casadevall
Rickey E. Carter
Michael J. Joyner
Mortality in individuals treated with COVID-19 convalescent plasma varies with the geographic provenance of donors
description Regional differences in SARS-CoV-2 variants may affect treatment outcome. Here, the authors show that near-sourced convalescent plasma has higher efficacy, as defined by death within 30 days of transfusion, than plasma sourced more than 150 miles away.
format article
author Katie L. Kunze
Patrick W. Johnson
Noud van Helmond
Jonathon W. Senefeld
Molly M. Petersen
Stephen A. Klassen
Chad C. Wiggins
Allan M. Klompas
Katelyn A. Bruno
John R. Mills
Elitza S. Theel
Matthew R. Buras
Michael A. Golafshar
Matthew A. Sexton
Juan C. Diaz Soto
Sarah E. Baker
John R. A. Shepherd
Nicole C. Verdun
Peter Marks
Nigel S. Paneth
DeLisa Fairweather
R. Scott Wright
Camille M. van Buskirk
Jeffrey L. Winters
James R. Stubbs
Katherine A. Senese
Michaela C. Pletsch
Zachary A. Buchholtz
Robert F. Rea
Vitaly Herasevich
Emily R. Whelan
Andrew J. Clayburn
Kathryn F. Larson
Juan G. Ripoll
Kylie J. Andersen
Elizabeth R. Lesser
Matthew N. P. Vogt
Joshua J. Dennis
Riley J. Regimbal
Philippe R. Bauer
Janis E. Blair
Arturo Casadevall
Rickey E. Carter
Michael J. Joyner
author_facet Katie L. Kunze
Patrick W. Johnson
Noud van Helmond
Jonathon W. Senefeld
Molly M. Petersen
Stephen A. Klassen
Chad C. Wiggins
Allan M. Klompas
Katelyn A. Bruno
John R. Mills
Elitza S. Theel
Matthew R. Buras
Michael A. Golafshar
Matthew A. Sexton
Juan C. Diaz Soto
Sarah E. Baker
John R. A. Shepherd
Nicole C. Verdun
Peter Marks
Nigel S. Paneth
DeLisa Fairweather
R. Scott Wright
Camille M. van Buskirk
Jeffrey L. Winters
James R. Stubbs
Katherine A. Senese
Michaela C. Pletsch
Zachary A. Buchholtz
Robert F. Rea
Vitaly Herasevich
Emily R. Whelan
Andrew J. Clayburn
Kathryn F. Larson
Juan G. Ripoll
Kylie J. Andersen
Elizabeth R. Lesser
Matthew N. P. Vogt
Joshua J. Dennis
Riley J. Regimbal
Philippe R. Bauer
Janis E. Blair
Arturo Casadevall
Rickey E. Carter
Michael J. Joyner
author_sort Katie L. Kunze
title Mortality in individuals treated with COVID-19 convalescent plasma varies with the geographic provenance of donors
title_short Mortality in individuals treated with COVID-19 convalescent plasma varies with the geographic provenance of donors
title_full Mortality in individuals treated with COVID-19 convalescent plasma varies with the geographic provenance of donors
title_fullStr Mortality in individuals treated with COVID-19 convalescent plasma varies with the geographic provenance of donors
title_full_unstemmed Mortality in individuals treated with COVID-19 convalescent plasma varies with the geographic provenance of donors
title_sort mortality in individuals treated with covid-19 convalescent plasma varies with the geographic provenance of donors
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/b4c2e18825314c909846a2c6aed3901d
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