Mortality in individuals treated with COVID-19 convalescent plasma varies with the geographic provenance of donors
Regional differences in SARS-CoV-2 variants may affect treatment outcome. Here, the authors show that near-sourced convalescent plasma has higher efficacy, as defined by death within 30 days of transfusion, than plasma sourced more than 150 miles away.
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2021
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oai:doaj.org-article:b4c2e18825314c909846a2c6aed3901d2021-12-02T18:50:57ZMortality in individuals treated with COVID-19 convalescent plasma varies with the geographic provenance of donors10.1038/s41467-021-25113-52041-1723https://doaj.org/article/b4c2e18825314c909846a2c6aed3901d2021-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-25113-5https://doaj.org/toc/2041-1723Regional differences in SARS-CoV-2 variants may affect treatment outcome. Here, the authors show that near-sourced convalescent plasma has higher efficacy, as defined by death within 30 days of transfusion, than plasma sourced more than 150 miles away.Katie L. KunzePatrick W. JohnsonNoud van HelmondJonathon W. SenefeldMolly M. PetersenStephen A. KlassenChad C. WigginsAllan M. KlompasKatelyn A. BrunoJohn R. MillsElitza S. TheelMatthew R. BurasMichael A. GolafsharMatthew A. SextonJuan C. Diaz SotoSarah E. BakerJohn R. A. ShepherdNicole C. VerdunPeter MarksNigel S. PanethDeLisa FairweatherR. Scott WrightCamille M. van BuskirkJeffrey L. WintersJames R. StubbsKatherine A. SeneseMichaela C. PletschZachary A. BuchholtzRobert F. ReaVitaly HerasevichEmily R. WhelanAndrew J. ClayburnKathryn F. LarsonJuan G. RipollKylie J. AndersenElizabeth R. LesserMatthew N. P. VogtJoshua J. DennisRiley J. RegimbalPhilippe R. BauerJanis E. BlairArturo CasadevallRickey E. CarterMichael J. JoynerNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-6 (2021) |
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Science Q Katie L. Kunze Patrick W. Johnson Noud van Helmond Jonathon W. Senefeld Molly M. Petersen Stephen A. Klassen Chad C. Wiggins Allan M. Klompas Katelyn A. Bruno John R. Mills Elitza S. Theel Matthew R. Buras Michael A. Golafshar Matthew A. Sexton Juan C. Diaz Soto Sarah E. Baker John R. A. Shepherd Nicole C. Verdun Peter Marks Nigel S. Paneth DeLisa Fairweather R. Scott Wright Camille M. van Buskirk Jeffrey L. Winters James R. Stubbs Katherine A. Senese Michaela C. Pletsch Zachary A. Buchholtz Robert F. Rea Vitaly Herasevich Emily R. Whelan Andrew J. Clayburn Kathryn F. Larson Juan G. Ripoll Kylie J. Andersen Elizabeth R. Lesser Matthew N. P. Vogt Joshua J. Dennis Riley J. Regimbal Philippe R. Bauer Janis E. Blair Arturo Casadevall Rickey E. Carter Michael J. Joyner Mortality in individuals treated with COVID-19 convalescent plasma varies with the geographic provenance of donors |
description |
Regional differences in SARS-CoV-2 variants may affect treatment outcome. Here, the authors show that near-sourced convalescent plasma has higher efficacy, as defined by death within 30 days of transfusion, than plasma sourced more than 150 miles away. |
format |
article |
author |
Katie L. Kunze Patrick W. Johnson Noud van Helmond Jonathon W. Senefeld Molly M. Petersen Stephen A. Klassen Chad C. Wiggins Allan M. Klompas Katelyn A. Bruno John R. Mills Elitza S. Theel Matthew R. Buras Michael A. Golafshar Matthew A. Sexton Juan C. Diaz Soto Sarah E. Baker John R. A. Shepherd Nicole C. Verdun Peter Marks Nigel S. Paneth DeLisa Fairweather R. Scott Wright Camille M. van Buskirk Jeffrey L. Winters James R. Stubbs Katherine A. Senese Michaela C. Pletsch Zachary A. Buchholtz Robert F. Rea Vitaly Herasevich Emily R. Whelan Andrew J. Clayburn Kathryn F. Larson Juan G. Ripoll Kylie J. Andersen Elizabeth R. Lesser Matthew N. P. Vogt Joshua J. Dennis Riley J. Regimbal Philippe R. Bauer Janis E. Blair Arturo Casadevall Rickey E. Carter Michael J. Joyner |
author_facet |
Katie L. Kunze Patrick W. Johnson Noud van Helmond Jonathon W. Senefeld Molly M. Petersen Stephen A. Klassen Chad C. Wiggins Allan M. Klompas Katelyn A. Bruno John R. Mills Elitza S. Theel Matthew R. Buras Michael A. Golafshar Matthew A. Sexton Juan C. Diaz Soto Sarah E. Baker John R. A. Shepherd Nicole C. Verdun Peter Marks Nigel S. Paneth DeLisa Fairweather R. Scott Wright Camille M. van Buskirk Jeffrey L. Winters James R. Stubbs Katherine A. Senese Michaela C. Pletsch Zachary A. Buchholtz Robert F. Rea Vitaly Herasevich Emily R. Whelan Andrew J. Clayburn Kathryn F. Larson Juan G. Ripoll Kylie J. Andersen Elizabeth R. Lesser Matthew N. P. Vogt Joshua J. Dennis Riley J. Regimbal Philippe R. Bauer Janis E. Blair Arturo Casadevall Rickey E. Carter Michael J. Joyner |
author_sort |
Katie L. Kunze |
title |
Mortality in individuals treated with COVID-19 convalescent plasma varies with the geographic provenance of donors |
title_short |
Mortality in individuals treated with COVID-19 convalescent plasma varies with the geographic provenance of donors |
title_full |
Mortality in individuals treated with COVID-19 convalescent plasma varies with the geographic provenance of donors |
title_fullStr |
Mortality in individuals treated with COVID-19 convalescent plasma varies with the geographic provenance of donors |
title_full_unstemmed |
Mortality in individuals treated with COVID-19 convalescent plasma varies with the geographic provenance of donors |
title_sort |
mortality in individuals treated with covid-19 convalescent plasma varies with the geographic provenance of donors |
publisher |
Nature Portfolio |
publishDate |
2021 |
url |
https://doaj.org/article/b4c2e18825314c909846a2c6aed3901d |
work_keys_str_mv |
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