A highly sensitive method for the detection of recombinant PERV-A/C env RNA using next generation sequencing technologies

Abstract Several xenogenic cell-based therapeutic products are currently under development around the world for the treatment of human diseases. Porcine islet cell products for treating human diabetes are a typical example. Since porcine cells possess endogenous retrovirus (PERV), which can replicat...

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Autores principales: Ken Kono, Kiyoko Kataoka, Yuzhe Yuan, Keisuke Yusa, Kazuhisa Uchida, Yoji Sato
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/b4ce8d8a941048a3b91f1d31adb3cd5c
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