Follicular-Stimulating Hormone, Luteinizing Hormone, and Prolactin Serum Level in Patients with Oral Lichen Planus in Comparison to Healthy Population

Aim and Background. Autoimmune diseases are more common in women; also, some relations have been reported between some sexual hormones and autoimmune diseases. In this study, we aimed to evaluate any possible relation of FSH, LH, and prolactin level and oral lichen planus (OLP). Materials and Method...

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Autores principales: Fatemeh Lavaee, Nazila Bazrafkan, Fateme Zarei, Maryam Shahrokhi Sardo
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Lenguaje:EN
Publicado: Hindawi Limited 2021
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Acceso en línea:https://doaj.org/article/b4daf49900024bc5b21cda4f42278674
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spelling oai:doaj.org-article:b4daf49900024bc5b21cda4f422786742021-11-08T02:35:27ZFollicular-Stimulating Hormone, Luteinizing Hormone, and Prolactin Serum Level in Patients with Oral Lichen Planus in Comparison to Healthy Population2314-614110.1155/2021/8679505https://doaj.org/article/b4daf49900024bc5b21cda4f422786742021-01-01T00:00:00Zhttp://dx.doi.org/10.1155/2021/8679505https://doaj.org/toc/2314-6141Aim and Background. Autoimmune diseases are more common in women; also, some relations have been reported between some sexual hormones and autoimmune diseases. In this study, we aimed to evaluate any possible relation of FSH, LH, and prolactin level and oral lichen planus (OLP). Materials and Methods. In this cross-sectional case control study, the serum level of LH, FSH, and prolactin of 40 women with lichen planus who have been referred to Shiraz Dental Faculty, Oral and Maxillofacial Disease Department during 2018-2019 has been evaluated in comparison to 40 healthy controls. Data were analyzed by SPSS version 18. Two-way ANOVA and Mann–Whitney test were used for data analysis. Results. The mean serum level of FSH and LH was significantly higher in OLP patients while this difference was not reported for prolactin. Only FSH mean serum level was significantly higher in nonmenopausal OLP patients. The distribution of prolactin and FSH hormones’ serum level was in normal range. Conclusions. The high serum level of FSH and LH can affect OLP pathogenesis by estrogen and progesterone modulation.Fatemeh LavaeeNazila BazrafkanFateme ZareiMaryam Shahrokhi SardoHindawi LimitedarticleMedicineRENBioMed Research International, Vol 2021 (2021)
institution DOAJ
collection DOAJ
language EN
topic Medicine
R
spellingShingle Medicine
R
Fatemeh Lavaee
Nazila Bazrafkan
Fateme Zarei
Maryam Shahrokhi Sardo
Follicular-Stimulating Hormone, Luteinizing Hormone, and Prolactin Serum Level in Patients with Oral Lichen Planus in Comparison to Healthy Population
description Aim and Background. Autoimmune diseases are more common in women; also, some relations have been reported between some sexual hormones and autoimmune diseases. In this study, we aimed to evaluate any possible relation of FSH, LH, and prolactin level and oral lichen planus (OLP). Materials and Methods. In this cross-sectional case control study, the serum level of LH, FSH, and prolactin of 40 women with lichen planus who have been referred to Shiraz Dental Faculty, Oral and Maxillofacial Disease Department during 2018-2019 has been evaluated in comparison to 40 healthy controls. Data were analyzed by SPSS version 18. Two-way ANOVA and Mann–Whitney test were used for data analysis. Results. The mean serum level of FSH and LH was significantly higher in OLP patients while this difference was not reported for prolactin. Only FSH mean serum level was significantly higher in nonmenopausal OLP patients. The distribution of prolactin and FSH hormones’ serum level was in normal range. Conclusions. The high serum level of FSH and LH can affect OLP pathogenesis by estrogen and progesterone modulation.
format article
author Fatemeh Lavaee
Nazila Bazrafkan
Fateme Zarei
Maryam Shahrokhi Sardo
author_facet Fatemeh Lavaee
Nazila Bazrafkan
Fateme Zarei
Maryam Shahrokhi Sardo
author_sort Fatemeh Lavaee
title Follicular-Stimulating Hormone, Luteinizing Hormone, and Prolactin Serum Level in Patients with Oral Lichen Planus in Comparison to Healthy Population
title_short Follicular-Stimulating Hormone, Luteinizing Hormone, and Prolactin Serum Level in Patients with Oral Lichen Planus in Comparison to Healthy Population
title_full Follicular-Stimulating Hormone, Luteinizing Hormone, and Prolactin Serum Level in Patients with Oral Lichen Planus in Comparison to Healthy Population
title_fullStr Follicular-Stimulating Hormone, Luteinizing Hormone, and Prolactin Serum Level in Patients with Oral Lichen Planus in Comparison to Healthy Population
title_full_unstemmed Follicular-Stimulating Hormone, Luteinizing Hormone, and Prolactin Serum Level in Patients with Oral Lichen Planus in Comparison to Healthy Population
title_sort follicular-stimulating hormone, luteinizing hormone, and prolactin serum level in patients with oral lichen planus in comparison to healthy population
publisher Hindawi Limited
publishDate 2021
url https://doaj.org/article/b4daf49900024bc5b21cda4f42278674
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