The role of axonal Kv1 channels in CA3 pyramidal cell excitability

The role of axonal Kv1 channels in CA3 pyramidal cell excitability

Abstract Axonal ion channels control spike initiation and propagation along the axon and determine action potential waveform. We show here that functional suppression of axonal Kv1 channels with local puff of dendrotoxin (DTx), laser or mechanical axotomy significantly increased excitability measure...

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Autores principales: Sylvain Rama, Mickael Zbili, Aurélie Fékété, Mónica Tapia, Maria José Benitez, Norah Boumedine, Juan José Garrido, Dominique Debanne
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/b4e80117a02f4e5d86fe9015fa2624b5
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