Difluorocarbene enables to access 2-fluoroindoles from ortho-vinylanilines

2-Fluoroindoles are an important structural scaffold in many bioactive or therapeutic agents, but efficient constructions of 2-fluoroindole derivatives are very sparce. Here the authors report an efficient and general strategy for the construction of 2-fluoroindoles in which a wide variety of 2-fluo...

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Autores principales:	Jianke Su, Xinyuan Hu, Hua Huang, Yu Guo, Qiuling Song
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/b4f06b0e23554d8d98d302d48e9c4054
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spelling	oai:doaj.org-article:b4f06b0e23554d8d98d302d48e9c40542021-12-02T18:00:08ZDifluorocarbene enables to access 2-fluoroindoles from ortho-vinylanilines10.1038/s41467-021-25313-z2041-1723https://doaj.org/article/b4f06b0e23554d8d98d302d48e9c40542021-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-25313-zhttps://doaj.org/toc/2041-17232-Fluoroindoles are an important structural scaffold in many bioactive or therapeutic agents, but efficient constructions of 2-fluoroindole derivatives are very sparce. Here the authors report an efficient and general strategy for the construction of 2-fluoroindoles in which a wide variety of 2-fluoroindoles were accessed with high efficiency and chemoselectivity.Jianke SuXinyuan HuHua HuangYu GuoQiuling SongNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-10 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Jianke Su Xinyuan Hu Hua Huang Yu Guo Qiuling Song Difluorocarbene enables to access 2-fluoroindoles from ortho-vinylanilines
description	2-Fluoroindoles are an important structural scaffold in many bioactive or therapeutic agents, but efficient constructions of 2-fluoroindole derivatives are very sparce. Here the authors report an efficient and general strategy for the construction of 2-fluoroindoles in which a wide variety of 2-fluoroindoles were accessed with high efficiency and chemoselectivity.
format	article
author	Jianke Su Xinyuan Hu Hua Huang Yu Guo Qiuling Song
author_facet	Jianke Su Xinyuan Hu Hua Huang Yu Guo Qiuling Song
author_sort	Jianke Su
title	Difluorocarbene enables to access 2-fluoroindoles from ortho-vinylanilines
title_short	Difluorocarbene enables to access 2-fluoroindoles from ortho-vinylanilines
title_full	Difluorocarbene enables to access 2-fluoroindoles from ortho-vinylanilines
title_fullStr	Difluorocarbene enables to access 2-fluoroindoles from ortho-vinylanilines
title_full_unstemmed	Difluorocarbene enables to access 2-fluoroindoles from ortho-vinylanilines
title_sort	difluorocarbene enables to access 2-fluoroindoles from ortho-vinylanilines
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/b4f06b0e23554d8d98d302d48e9c4054
work_keys_str_mv	AT jiankesu difluorocarbeneenablestoaccess2fluoroindolesfromorthovinylanilines AT xinyuanhu difluorocarbeneenablestoaccess2fluoroindolesfromorthovinylanilines AT huahuang difluorocarbeneenablestoaccess2fluoroindolesfromorthovinylanilines AT yuguo difluorocarbeneenablestoaccess2fluoroindolesfromorthovinylanilines AT qiulingsong difluorocarbeneenablestoaccess2fluoroindolesfromorthovinylanilines
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Difluorocarbene enables to access 2-fluoroindoles from ortho-vinylanilines

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