Inhibition of extracellular signal-regulated kinase pathway suppresses tracheal stenosis in a novel mouse model.

Tracheal stenosis is a refractory and recurrent disease induced by excessive cell proliferation within the restricted tracheal space. We investigated the role of extracellular signal-regulated kinase (ERK), which mediates a broad range of intracellular signal transduction processes in tracheal steno...

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Autores principales: Akari Kimura, Koji Araki, Yasushi Satoh, Sachiyo Mogi, Kazuko Fujitani, Takaomi Kurioka, Shogo Endo, Akihiro Shiotani, Taku Yamashita
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2021
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Acceso en línea:https://doaj.org/article/b4fc6ab9f6cc4ed390cfdc81d7d1c287
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