Advances in stent technologies and their effect on clinical efficacy and safety

Navin Nikam, Toby B Steinberg, Daniel H SteinbergDivision of Cardiology, Medical University of South Carolina, Charleston, SC, USAAbstract: The introduction of intracoronary stents represented a major advance in interventional cardiology. While bare metal stents set the benchmark for improved safet...

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Autores principales:	Nikam N, Steinberg TB, Steinberg DH
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2014
Materias:	Medical technology R855-855.5
Acceso en línea:	https://doaj.org/article/b506b6263a17476eb8d26185b67f4fb7
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spelling	oai:doaj.org-article:b506b6263a17476eb8d26185b67f4fb72021-12-02T05:59:21ZAdvances in stent technologies and their effect on clinical efficacy and safety1179-1470https://doaj.org/article/b506b6263a17476eb8d26185b67f4fb72014-06-01T00:00:00Zhttp://www.dovepress.com/advances-in-stent-technologies-and-their-effect-on-clinical-efficacy-a-a17090https://doaj.org/toc/1179-1470 Navin Nikam, Toby B Steinberg, Daniel H SteinbergDivision of Cardiology, Medical University of South Carolina, Charleston, SC, USAAbstract: The introduction of intracoronary stents represented a major advance in interventional cardiology. While bare metal stents set the benchmark for improved safety over angioplasty, intimal hyperplasia and subsequent restenosis were important limitations. First-generation drug-eluting stents demonstrated significant improvements in efficacy, but not necessarily safety, and further technologic developments have focused on optimizing both. Current advances and understanding in stent design continue to improve on these concepts. This review summarizes past and present technology with particular emphasis on the principles underlying the efficacy and safety of drug-eluting stents, and offers a glimpse into the next generations of stents aimed at treating symptomatic coronary artery disease.Keywords: drug-eluting stents percutaneous coronary intervention, coronary artery disease, bioabsorbable polymers, bioabsorbable struts, polymer freeNikam NSteinberg TBSteinberg DHDove Medical PressarticleMedical technologyR855-855.5ENMedical Devices: Evidence and Research, Vol 2014, Iss default, Pp 165-178 (2014)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medical technology R855-855.5
spellingShingle	Medical technology R855-855.5 Nikam N Steinberg TB Steinberg DH Advances in stent technologies and their effect on clinical efficacy and safety
description	Navin Nikam, Toby B Steinberg, Daniel H SteinbergDivision of Cardiology, Medical University of South Carolina, Charleston, SC, USAAbstract: The introduction of intracoronary stents represented a major advance in interventional cardiology. While bare metal stents set the benchmark for improved safety over angioplasty, intimal hyperplasia and subsequent restenosis were important limitations. First-generation drug-eluting stents demonstrated significant improvements in efficacy, but not necessarily safety, and further technologic developments have focused on optimizing both. Current advances and understanding in stent design continue to improve on these concepts. This review summarizes past and present technology with particular emphasis on the principles underlying the efficacy and safety of drug-eluting stents, and offers a glimpse into the next generations of stents aimed at treating symptomatic coronary artery disease.Keywords: drug-eluting stents percutaneous coronary intervention, coronary artery disease, bioabsorbable polymers, bioabsorbable struts, polymer free
format	article
author	Nikam N Steinberg TB Steinberg DH
author_facet	Nikam N Steinberg TB Steinberg DH
author_sort	Nikam N
title	Advances in stent technologies and their effect on clinical efficacy and safety
title_short	Advances in stent technologies and their effect on clinical efficacy and safety
title_full	Advances in stent technologies and their effect on clinical efficacy and safety
title_fullStr	Advances in stent technologies and their effect on clinical efficacy and safety
title_full_unstemmed	Advances in stent technologies and their effect on clinical efficacy and safety
title_sort	advances in stent technologies and their effect on clinical efficacy and safety
publisher	Dove Medical Press
publishDate	2014
url	https://doaj.org/article/b506b6263a17476eb8d26185b67f4fb7
work_keys_str_mv	AT nikamn advancesinstenttechnologiesandtheireffectonclinicalefficacyandsafety AT steinbergtb advancesinstenttechnologiesandtheireffectonclinicalefficacyandsafety AT steinbergdh advancesinstenttechnologiesandtheireffectonclinicalefficacyandsafety
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Advances in stent technologies and their effect on clinical efficacy and safety

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