Identification of Spacer and Protospacer Sequence Requirements in the <named-content content-type="genus-species">Vibrio cholerae</named-content> Type I-E CRISPR/Cas System
ABSTRACT The prokaryotic adaptive immune system CRISPR/Cas serves as a defense against bacteriophage and invasive nucleic acids. A type I-E CRISPR/Cas system has been detected in classical biotype isolates of Vibrio cholerae, the causative agent of the disease cholera. Experimental characterization...
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Main Authors: | Jacob Bourgeois, David W. Lazinski, Andrew Camilli |
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Format: | article |
Language: | EN |
Published: |
American Society for Microbiology
2020
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Subjects: | |
Online Access: | https://doaj.org/article/b5078ad07bd74247a873242366bee82a |
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