Identification of Spacer and Protospacer Sequence Requirements in the <named-content content-type="genus-species">Vibrio cholerae</named-content> Type I-E CRISPR/Cas System

Identification of Spacer and Protospacer Sequence Requirements in the <named-content content-type="genus-species">Vibrio cholerae</named-content> Type I-E CRISPR/Cas System

ABSTRACT The prokaryotic adaptive immune system CRISPR/Cas serves as a defense against bacteriophage and invasive nucleic acids. A type I-E CRISPR/Cas system has been detected in classical biotype isolates of Vibrio cholerae, the causative agent of the disease cholera. Experimental characterization...

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Autores principales: Jacob Bourgeois, David W. Lazinski, Andrew Camilli
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2020
Materias:
CRISPR/Cas
Vibrio cholerae
protospacer-adjacent motif
Microbiology
QR1-502
Acceso en línea:https://doaj.org/article/b5078ad07bd74247a873242366bee82a
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