Evidence for a âpreinvasiveâ variant of fungal sinusitis: Tissue invasion without angioinvasion

Clinical experience has suggested the existence of an intermediate form of fungal sinusitis between the categories of non-invasive fungal sinusitis (non-IFS) and invasive fungal sinusitis (IFS). This fungal sinusitis variant demonstrates unhealthy mucosa by endoscopy with fungal invasion, but lacks...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Hassan Paknezhad, Nicole A. Borchard, Greg W. Charville, Noel F. Ayoub, Garret W. Choby, Andrew Thamboo, Jayakar V. Nayak
Formato:	article
Lenguaje:	EN
Publicado:	KeAi Communications Co., Ltd. 2017
Materias:	Otorhinolaryngology RF1-547 Surgery RD1-811
Acceso en línea:	https://doaj.org/article/b50c0f38ace74b9b88d7aff22a22e195
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:b50c0f38ace74b9b88d7aff22a22e195
record_format	dspace
spelling	oai:doaj.org-article:b50c0f38ace74b9b88d7aff22a22e1952021-12-02T10:50:49ZEvidence for a âpreinvasiveâ variant of fungal sinusitis: Tissue invasion without angioinvasion2095-881110.1016/j.wjorl.2017.01.003https://doaj.org/article/b50c0f38ace74b9b88d7aff22a22e1952017-03-01T00:00:00Zhttp://www.sciencedirect.com/science/article/pii/S2095881117300094https://doaj.org/toc/2095-8811Clinical experience has suggested the existence of an intermediate form of fungal sinusitis between the categories of non-invasive fungal sinusitis (non-IFS) and invasive fungal sinusitis (IFS). This fungal sinusitis variant demonstrates unhealthy mucosa by endoscopy with fungal invasion, but lacks angioinvasion microscopically, representing what clinically behaves as a âpre-invasiveâ subtype of fungal sinusitis. Unlike non-IFS disease, patients with pre-invasive fungal sinusitis were still felt to require anti-fungal medications due to histologic presence of invasive fungus. While sharing some clinical features of IFS, these âintermediateâ patients were successfully spared extended and repeated surgical debridements given the microscopic findings, and have been successfully treated with shorter courses of antifungal therapy. These select patients have had favorable outcomes when managed in a judicious and semi-aggressive manner, in an undefined zone between the treatments for routine fungal ball and aggressive IFS. Keywords: Fungal sinusitis, Invasive fungal sinusitis, IFS, Chronic rhinosinusitis, Fungal ball, Visual loss, Immunocompromised, Immunosuppressed, Antifungal therapyHassan PaknezhadNicole A. BorchardGreg W. CharvilleNoel F. AyoubGarret W. ChobyAndrew ThambooJayakar V. NayakKeAi Communications Co., Ltd.articleOtorhinolaryngologyRF1-547SurgeryRD1-811ENWorld Journal of Otorhinolaryngology-Head and Neck Surgery, Vol 3, Iss 1, Pp 37-43 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Otorhinolaryngology RF1-547 Surgery RD1-811
spellingShingle	Otorhinolaryngology RF1-547 Surgery RD1-811 Hassan Paknezhad Nicole A. Borchard Greg W. Charville Noel F. Ayoub Garret W. Choby Andrew Thamboo Jayakar V. Nayak Evidence for a âpreinvasiveâ variant of fungal sinusitis: Tissue invasion without angioinvasion
description	Clinical experience has suggested the existence of an intermediate form of fungal sinusitis between the categories of non-invasive fungal sinusitis (non-IFS) and invasive fungal sinusitis (IFS). This fungal sinusitis variant demonstrates unhealthy mucosa by endoscopy with fungal invasion, but lacks angioinvasion microscopically, representing what clinically behaves as a âpre-invasiveâ subtype of fungal sinusitis. Unlike non-IFS disease, patients with pre-invasive fungal sinusitis were still felt to require anti-fungal medications due to histologic presence of invasive fungus. While sharing some clinical features of IFS, these âintermediateâ patients were successfully spared extended and repeated surgical debridements given the microscopic findings, and have been successfully treated with shorter courses of antifungal therapy. These select patients have had favorable outcomes when managed in a judicious and semi-aggressive manner, in an undefined zone between the treatments for routine fungal ball and aggressive IFS. Keywords: Fungal sinusitis, Invasive fungal sinusitis, IFS, Chronic rhinosinusitis, Fungal ball, Visual loss, Immunocompromised, Immunosuppressed, Antifungal therapy
format	article
author	Hassan Paknezhad Nicole A. Borchard Greg W. Charville Noel F. Ayoub Garret W. Choby Andrew Thamboo Jayakar V. Nayak
author_facet	Hassan Paknezhad Nicole A. Borchard Greg W. Charville Noel F. Ayoub Garret W. Choby Andrew Thamboo Jayakar V. Nayak
author_sort	Hassan Paknezhad
title	Evidence for a âpreinvasiveâ variant of fungal sinusitis: Tissue invasion without angioinvasion
title_short	Evidence for a âpreinvasiveâ variant of fungal sinusitis: Tissue invasion without angioinvasion
title_full	Evidence for a âpreinvasiveâ variant of fungal sinusitis: Tissue invasion without angioinvasion
title_fullStr	Evidence for a âpreinvasiveâ variant of fungal sinusitis: Tissue invasion without angioinvasion
title_full_unstemmed	Evidence for a âpreinvasiveâ variant of fungal sinusitis: Tissue invasion without angioinvasion
title_sort	evidence for a âpreinvasiveâ variant of fungal sinusitis: tissue invasion without angioinvasion
publisher	KeAi Communications Co., Ltd.
publishDate	2017
url	https://doaj.org/article/b50c0f38ace74b9b88d7aff22a22e195
work_keys_str_mv	AT hassanpaknezhad evidenceforaapreinvasiveavariantoffungalsinusitistissueinvasionwithoutangioinvasion AT nicoleaborchard evidenceforaapreinvasiveavariantoffungalsinusitistissueinvasionwithoutangioinvasion AT gregwcharville evidenceforaapreinvasiveavariantoffungalsinusitistissueinvasionwithoutangioinvasion AT noelfayoub evidenceforaapreinvasiveavariantoffungalsinusitistissueinvasionwithoutangioinvasion AT garretwchoby evidenceforaapreinvasiveavariantoffungalsinusitistissueinvasionwithoutangioinvasion AT andrewthamboo evidenceforaapreinvasiveavariantoffungalsinusitistissueinvasionwithoutangioinvasion AT jayakarvnayak evidenceforaapreinvasiveavariantoffungalsinusitistissueinvasionwithoutangioinvasion
_version_	1718396551819165696

Evidence for a âpreinvasiveâ variant of fungal sinusitis: Tissue invasion without angioinvasion

Ejemplares similares