Prevention of CaCl2-induced aortic inflammation and subsequent aneurysm formation by the CCL3–CCR5 axis

Inflammatory cytokines and chemokines are involved in the development of abdominal aortic aneurysm (AAA). Here the authors show that CCL3 prevents the development of CaCl2-induced AAA by suppressing MMP-9 expression.

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Autores principales:	Yuko Ishida, Yumi Kuninaka, Mizuho Nosaka, Akihiko Kimura, Akira Taruya, Machi Furuta, Naofumi Mukaida, Toshikazu Kondo
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/b5159cd2526e4773a1ea9ce2d906649e
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spelling	oai:doaj.org-article:b5159cd2526e4773a1ea9ce2d906649e2021-12-02T13:57:33ZPrevention of CaCl2-induced aortic inflammation and subsequent aneurysm formation by the CCL3–CCR5 axis10.1038/s41467-020-19763-02041-1723https://doaj.org/article/b5159cd2526e4773a1ea9ce2d906649e2020-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-19763-0https://doaj.org/toc/2041-1723Inflammatory cytokines and chemokines are involved in the development of abdominal aortic aneurysm (AAA). Here the authors show that CCL3 prevents the development of CaCl2-induced AAA by suppressing MMP-9 expression.Yuko IshidaYumi KuninakaMizuho NosakaAkihiko KimuraAkira TaruyaMachi FurutaNaofumi MukaidaToshikazu KondoNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Yuko Ishida Yumi Kuninaka Mizuho Nosaka Akihiko Kimura Akira Taruya Machi Furuta Naofumi Mukaida Toshikazu Kondo Prevention of CaCl2-induced aortic inflammation and subsequent aneurysm formation by the CCL3–CCR5 axis
description	Inflammatory cytokines and chemokines are involved in the development of abdominal aortic aneurysm (AAA). Here the authors show that CCL3 prevents the development of CaCl2-induced AAA by suppressing MMP-9 expression.
format	article
author	Yuko Ishida Yumi Kuninaka Mizuho Nosaka Akihiko Kimura Akira Taruya Machi Furuta Naofumi Mukaida Toshikazu Kondo
author_facet	Yuko Ishida Yumi Kuninaka Mizuho Nosaka Akihiko Kimura Akira Taruya Machi Furuta Naofumi Mukaida Toshikazu Kondo
author_sort	Yuko Ishida
title	Prevention of CaCl2-induced aortic inflammation and subsequent aneurysm formation by the CCL3–CCR5 axis
title_short	Prevention of CaCl2-induced aortic inflammation and subsequent aneurysm formation by the CCL3–CCR5 axis
title_full	Prevention of CaCl2-induced aortic inflammation and subsequent aneurysm formation by the CCL3–CCR5 axis
title_fullStr	Prevention of CaCl2-induced aortic inflammation and subsequent aneurysm formation by the CCL3–CCR5 axis
title_full_unstemmed	Prevention of CaCl2-induced aortic inflammation and subsequent aneurysm formation by the CCL3–CCR5 axis
title_sort	prevention of cacl2-induced aortic inflammation and subsequent aneurysm formation by the ccl3–ccr5 axis
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/b5159cd2526e4773a1ea9ce2d906649e
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Prevention of CaCl2-induced aortic inflammation and subsequent aneurysm formation by the CCL3–CCR5 axis

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