Prevention of CaCl2-induced aortic inflammation and subsequent aneurysm formation by the CCL3–CCR5 axis

Inflammatory cytokines and chemokines are involved in the development of abdominal aortic aneurysm (AAA). Here the authors show that CCL3 prevents the development of CaCl2-induced AAA by suppressing MMP-9 expression.

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Auteurs principaux: Yuko Ishida, Yumi Kuninaka, Mizuho Nosaka, Akihiko Kimura, Akira Taruya, Machi Furuta, Naofumi Mukaida, Toshikazu Kondo
Format: article
Langue:EN
Publié: Nature Portfolio 2020
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Accès en ligne:https://doaj.org/article/b5159cd2526e4773a1ea9ce2d906649e
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