Phosphorylation modifies the molecular stability of β-amyloid deposits
Protein aggregation plays a crucial role in several neurodegenerative diseases. Here the authors demonstrate that phosphorylation of β-amyloid aggregates—the pathological hallmark of Alzheimer's disease—can change the molecular properties of aggregates, suggesting how phosphorylation contribute...
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Main Authors: | Nasrollah Rezaei-Ghaleh, Mehriar Amininasab, Sathish Kumar, Jochen Walter, Markus Zweckstetter |
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Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2016
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Online Access: | https://doaj.org/article/b51e7f2b30e242a2be7281a13feadd10 |
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