IQGAP1 Is Important for Activation of Caspase-1 in Macrophages and Is Targeted by <named-content content-type="genus-species">Yersinia pestis</named-content> Type III Effector YopM

IQGAP1 Is Important for Activation of Caspase-1 in Macrophages and Is Targeted by <named-content content-type="genus-species">Yersinia pestis</named-content> Type III Effector YopM

ABSTRACT YopM is a leucine-rich repeat (LRR)-containing effector in several Yersinia species, including Yersinia pestis and Y. pseudotuberculosis. Different Yersinia strains encode distinct YopM isoforms with variable numbers of LRRs but conserved C-terminal tails. A 15-LRR isoform in Y. pseudotuber...

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Autores principales: Lawton K. Chung, Naomi H. Philip, Valentina A. Schmidt, Antonius Koller, Till Strowig, Richard A. Flavell, Igor E. Brodsky, James B. Bliska
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2014
Materias:
Microbiology
QR1-502
Acceso en línea:https://doaj.org/article/b52107ccd381415e9be79f32f4afdd51
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